Ratan Banik, MD, PhD
Administrative Contact
Ashley Neumann
Administrative Associate 1
[email protected]
Address
B515 Mayo Memorial Building,
420 Delaware Street SE,
Minneapolis, MN 55455
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Biography
Dr. Ratan Banik is an associate professor in the Department of Anesthesiology. His research focuses on postoperative pain following surgical incision, which includes behavioral phenotypes, peripheral nociceptor sensitization, and pharmacologic modulation. To understand genomic effects associated pain behaviors after surgery, he performs transcriptomic analysis of rat dorsal root ganglia using state-of-the-art next-generation sequencing. The approach permits the assessment of all genes expressed in the primary afferent neurons, uncovering gene dysregulation and respective molecular networks critical for the development of postoperative pain. Ongoing studies are aimed at identifying a novel pharmacologic target with high therapeutic potential in postoperative pain.
Dr. Banik's clinical interests are to help patients achieve functional restoration and improved quality of life through an effective multidisciplinary approach to pain management.
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Education
Fellowship in Pain Medicine, MD Anderson Cancer Center
Residency in Anesthesiology, Albert Einstein College of Medicine
Postdoctoral Research Fellowship, University of Iowa
PhD, Nagoya University
MD, Dhaka University
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Publications
Banik, R. K., Sia, T., Johns, M. E., Tran, P. V., Cheng, A. Y., Setty, S., & Simone, D. A. (2024). Methylene blue dose-dependently induces cutaneous inflammation and heat hyperalgesia in a novel rat model. Molecular Pain, 20. https://doi.org/10.1177/17448069241259535
Banik, R. K., Tran, B. W., Belfar, A., Akhtaruzzaman, A. K. M., Nada, E., & Hanson, N. (2024). Therapeutic efficacy of intravenous lidocaine infusion compared with thoracic epidural analgesia in major abdominal surgery: factors affecting successful thoracic epidural analgesia. Comment on Br J Anaesth 2023; 131: 947–54. British Journal of Anaesthesia, 132(5), 1169-1170. https://doi.org/10.1016/j.bja.2024.01.008
Banik, R. K., Sia, T., Ibrahim, M. M., Sivanesan, E., Uhelski, M., Pena, A., Streicher, J. M., & Simone, D. A. (2023). Increases in local skin temperature correlate with spontaneous foot lifting and heat hyperalgesia in both incisional inflammatory models of pain. Pain Reports, 8(5), E1097. https://doi.org/10.1097/PR9.0000000000001097
Banik, R. K., Peng, S., Kohan, L., Rana, P., Darrow, D. P., & Hagedorn, J. M. (2023). Radiofrequency Ablation of Lumbar Medial Branch Nerves in a Patient with a Deep Brain Stimulator: Our Experience and Literature Review. Pain Medicine (United States), 24(6), 734-737. https://doi.org/10.1093/pm/pnac179
Banik, R. K., Peng, S., Hussain, N., Goel, V., Hagedorn, J. M., Chai, T., Anitescu, M., & Fillingim, R. B. (2023). The Relationship Between Chronic Pain and Cognitive Decline in Older Population: A Cautionary Tale from Current Literature. Pain Medicine (United States), 24(2), 110-112. https://doi.org/10.1093/pm/pnac144
Uhelski, M. L., Johns, M. E., Horrmann, A., Mohamed, S., Sohail, A., Khasabova, I. A., Simone, D. A., & Banik, R. K. (2022). Adverse effects of methylene blue in peripheral neurons: An in vitro electrophysiology and cell culture study. Molecular Pain, 18. https://doi.org/10.1177/17448069221142523
Banik, R. K. (2022). Anesthesiology In-Training Exam Review: Regional Anesthesia and Chronic Pain. Springer International Publishing. https://doi.org/10.1007/978-3-030-87266-3
Bemel, B., Stalter, N., Mathiason, M. A., Banik, R., & Pruinelli, L. (2022). A Predictive Model for Developing Long-Term Opioid Use after Neurosurgery and Orthopedic Surgery. AANA Journal, 9(2), 114-120.
Averbakh, E., Chung, M., Banik, R. K., & Chai, T. (2022). Basic Science: Social, Vocational, and Psychological Influences on Pain Perception. In Anesthesiology In-Training Exam Review: Regional Anesthesia and Chronic Pain (pp. 197-201). Springer International Publishing. https://doi.org/10.1007/978-3-030-87266-3_38
Khatri, N., Hernandez, N., Grant, S., & Banik, R. K. (2022). Gender and Age Differences in Pain Perception. In Anesthesiology In-Training Exam Review: Regional Anesthesia and Chronic Pain (pp. 203-205). Springer International Publishing. https://doi.org/10.1007/978-3-030-87266-3_39
Palm, D., & Banik, R. K. (2022). General Topics: Local Anesthetic Systemic Toxicity. In Anesthesiology In-Training Exam Review: Regional Anesthesia and Chronic Pain (pp. 45-50). Springer International Publishing. https://doi.org/10.1007/978-3-030-87266-3_9
Bennett, C., & Banik, R. K. (2022). General Topics: Nerve Injury in Regional Anesthesia. In Anesthesiology In-Training Exam Review: Regional Anesthesia and Chronic Pain (pp. 37-40). Springer International Publishing. https://doi.org/10.1007/978-3-030-87266-3_7
DeWeerth, J. C., & Banik, R. K. (2022). Multimodal Analgesia for Chronic Pain. In Anesthesiology In-Training Exam Review: Regional Anesthesia and Chronic Pain (pp. 341-346). Springer International Publishing. https://doi.org/10.1007/978-3-030-87266-3_65
Goel, V., Yang, Y., Kanwar, S., Banik, R. K., Patwardhan, A. M., Ibrahim, M., Sivanesan, E., & Shankar, H. (2021). Adverse Events and Complications Associated With Intrathecal Drug Delivery Systems: Insights From the Manufacturer and User Facility Device Experience (MAUDE) Database. Neuromodulation, 24(7), 1181-1189. https://doi.org/10.1111/ner.13325
Banik, R. K., McDaniel, E., DeWeerth, J. C., & Sembrano, J. N. (2021). Iliocostal Friction Syndrome Due to Hair-Pin Shaped Thoracic Kyphosis. Pain Medicine (United States), 22(5), 1223-1224. https://doi.org/10.1093/pm/pnab027
Banik, R. K., Honeyfield, K., Qureshi, S., & Reddy, S. G. (2021). Incidence and Mortality Rate of Perioperative Reintubation: Case Series of 196 Patients. AANA Journal, 89(6), 476-479.
Goel, V., Patwardhan, A. M., Ibrahim, M., Yang, Y., Sivanesan, E., Banik, R. K., Shannon, C., & Shankar, H. (2021). Industry Payments to Pain Medicine Physicians: An Analysis of the Centers for Medicare and Medicaid Services Open Payments Program. Pain Medicine (United States), 22(6), 1376-1386. https://doi.org/10.1093/pm/pnaa450
Ishida, H., Zhang, Y., Gomez, R., Shannonhouse, J., Son, H., Banik, R., & Shin Kim, Y. (2021). In vivo calcium imaging visualizes incision-induced primary afferent sensitization and its amelioration by capsaicin pretreatment. Journal of Neuroscience, 41(41), 8494-8507. https://doi.org/10.1523/JNEUROSCI.0457-21.2021
Karuppiah, S., Prielipp, R., & Banik, R. K. (2020). Anesthetic consideration for patients with micra leadless pacemaker. Annals of Cardiac Anaesthesia, 23(4), 493-495. https://doi.org/10.4103/aca.ACA_191_19
Nadar, V., & Banik, R. K. (2020). Anesthetic Management for Emergent Repair of Tracheoinnominate Fistula. Case Reports in Anesthesiology, 2020, Article 8865303. https://doi.org/10.1155/2020/8865303
Banik, R. K., & Ulrich, A. (2020). Evidence of Short-Range Aerosol Transmission of SARS-CoV-2 and Call for Universal Airborne Precautions for Anesthesiologists During the COVID-19 Pandemic. Anesthesia and analgesia, 131(2), E102-E104. https://doi.org/10.1213/ANE.0000000000004933
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Research
Postoperative Pain
Aging and Pain
Molecular Mechanisms of Pain
Interdisciplinary Pain Management
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Awards, Honors and Recognitions
Grant reviewer: Italian Ministry of Health (in-collaboration with NIH), 2011
Grant Reviewer: University of Southern Nevada, 2010
American Pain Society Young Investigator Travel Award, 2008
American Pain Society Young Investigator Travel Award, 2004
Graduate student fellowship for foreign students by Ministry of Education, 1997
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Presentations
Jiminez-Ruiz, F., Banik, R. K. "Sugammadex and quantitative train of four monitoring may change anesthetic management in myasthenia gravis patients; a case report and discussion. ", American Society of Anesthesiology Annual meeting Abstract, American Society of Anesthesiology Annual meeting Abstract. January 01, 2018.
nader, v., (Author), Banik, R. K. "Splanchnic Nerve Radiofrequency Ablation for Chronic Flank Pain from Ureteral Pathology", American Society of Anesthesiology Annual meeting Abstract. January 01, 2018.
Waldera, J., Banik, R. K. "Fluoroscopy Guided Percutaneous Radiofrequency Ablation of Morton's Neuroma: A Step Beyond Interventional Pain Medicine", American Society of Anesthesiology Annual meeting Abstract. January 01, 2018.
Kim, P., Banik, R. K. "”Palliative Pain Control With An Erector Spinae Plane Catheter In A Patient With Metastatic Appendiceal Cancer.”". January 01, 2018.
Kim, P., Banik, R. K. "Lidocaine Infusions for Lower Extremity Cramping for Hypercalcemia", American Society of Anesthesiologists annual meeting . January 01, 2018.
Banik, R. K., Takeuchi, K. "Development of an iPhone App for Monitoring Intraoperative Neuromuscular blockade", American Society of Anesthesiology Annual Meeting Abstract, American Society of Anesthesiology, Boston, Massachusetts, United States. January 01, 2017.
Kim, P. Y., Banik, R. K. "Anterior Groin Pain after Total Hip Arthroplasty: Can this be Iliopsoas Tendinitis? A case report and discussion", American Society of Anesthesiology Annual meeting Abstract, American Society of Anesthesiology, Boston, Massachusetts, United States. January 01, 2017.
Banik, R. K., Kim, P. Y. "Corticosteroid-Induced Psychosis after a single Transforaminal Epidural Steroid Injection: A case report and discussion", American Society of Anesthesiology Annual Meeting Abstract, American Society of Anesthesiology, Boston, Massachusetts, United States. January 01, 2017.
Banik, R. K., Kim, P. Y., Barreda, B. "Great Auricular and Transverse Cervical Neuralgia after Carotid endarterectomy: A case report and discussion", American Society of Anesthesiology Annual Meeting Abstract, American Society of Anesthesiology, Boston, Massachusetts, United States. January 01, 2017.
Banik, R. K., Gallo, MD, P. D., Kim, MD, P. Y. "Scrotal Pain After Vasectomy: Can this be genitofemoral neuralgia? A case report and discussion", American Society of Anesthesiology Annual Meeting Abstract, American Society of Anesthesiology, Boston, Massachusetts, United States. January 01, 2017.
Banik, R. K. "Of rats and mice: a brief journey to the peripheral pain mechanisms", University of Alabama Visiting Professor lecture, University of Alabama, Birmingham, Alabama, United States. November 01, 2016.
Banik, R. K. "Scrambler therapy for chemotherapy induced neuropathic pain refractory to pharmacotherapy: a case report", World Congress of pain, New York City, New York, United States. May 01, 2016.
Banik, R. K., Huh, B., Kim, MD, P. Y. "Pain associated with melorheostosis refractory to pharmacotherapy and injections significantly improved with spinal cord simulation", North American Neuromodulation Society Annual Meeting, North American Neuromodulation Society, Las Vegas, Nevada, United States. January 01, 2016.
Banik, R. K., Gonzalez, J. "Single shot of ropivacaine, dexamethasone, lidocaine, and epinephrine given into the epidural space as sole anesthesia for Lumbar laminectomy surgery: A case report", ANESTH ANALG . January 01, 2015.
Banik, R. K., Qureshi, S., Reddy, S. R. "incidence and causes of perioperative reintubation: A review of 198 cases", ANESTH ANALG . January 01, 2015.
Banik, R. K., Kaliappan, S. "Age related changes in epidermal innervaation and nociception like behaviors", 13th World Congress of Pain, Montreal, Canada. August 01, 2010.
Banik, R. K., Kouya, F., Lqbal, Z. "Evalution of anxiety-like behaviors in a rat model of incisional pain", 13th World Congress of Pain , Montreal , Canada. August 01, 2010.
Banik, R. K., Kouya, P. F. "A modified hargreaves' method for measuring approximate threshold temperature for thermonociception", 13th World Congress of Pain, Montreal , Canada. August 01, 2010.
Banik, R. K., Somaiya, J., Przybylski, G. "Prevalence and etiology of radiculopathy in patients admitted in a community hospital of New Jersey over eight years", 13th World Congress of Pain, Montreal , Canada. August 01, 2010.
Banik, R. K., Kabadi, R., Kouya, F. "Spontaneous foot lifting behaviors after plantar incision in the rat: Attenuated by anti-ngf and completely abolished by buprenorphine and morphine in a dose-dependent manner.", 13th World Congress of Pain, Montreal , Canada. August 01, 2010.
Banik, R. K. "Prevalence and causes of radiculopathic pain", NJ Neuroscience Institute, Edison, New Jersey, United States. June 03, 2009.
Banik, R. K. "Postoperative pain mechanisms", Columbia University, New York City, New York, United States. April 01, 2009.
Banik, R. K. "Role of TrpV1 on postoperative pain", Department of Biological Sciences Baylor College of Dentistry, Dallas, Texas, United States. December 03, 2008.
Banik, R. K. "Clues from cuisine: how the receptor for hot chili pepper becomes a pain killing target", Department of Biological Sciences Seton Hall University , South Orange, New Jersey, United States. September 24, 2008.
Banik, R. K. "Receptor for hot sauce as a novel pain killing target", NJ Neuroscience Institute, Edison, New Jersey, United States. June 18, 2008.
Banik, R. K., Sagar, D., Chowdhury, S. "Electronic Medical Records: Application to the Pain Epidemiology", National Institute of Health Pain Consortium, Bethesda, Maryland, United States. May 22, 2008.
Banik, R. K., Sagar, D., Chowdhury, S. "Electronic Medical Records: Application to the Pain Epidemiology", Annual Meeting of the American Pain Society, Tampa, Florida, United States. January 01, 2008.
Banik, R. K., Linjing, X., Price, M., Subieta, A., Welsh, M., Brennan, T. "Mechanical responses of cutaneous afferents in ASIC triple KO mice", 12th World Congress on Pain, Glasgow, Scotland. January 01, 2008.
Banik, R. K. "Mechanisms of Neuropathic pain: what do we know?", NJ Neuroscience Institute, Edison, New Jersey, United States. June 24, 2007.
Banik, R. K., Kang, S., Brennan, T. "Effect of Subcutaneous capsaicin on mechanosensitive afferents in rat glabrous skin one day after plantar incsion", 2007 Neuroscience Meeting Planner, Society of Neuroscience, San Diego, California, United States. January 01, 2007.
Banik, R. K. "Role of TrpV1 in incisional pain mechanisms", Midwest pain symposium, Iowa City, Iowa, United States. May 16, 2006.
Banik, R. K. "Role TrpV1 in postoperative pain mechanisms", NJ Neuroscience Institute, JFK Medical Center, Edison, New Jersey, United States. May 05, 2006.
Banik, R. K. "TrpV1 in primary afferent terminals mediate postoperative heat hyperalgesia", Postdoctoral Workshop, University of Iowa , Department of Pharmacology, Iowa City, Iowa, United States. January 24, 2006.
Banik, R. K. "TrpV1 in primary afferent terminals mediates plantar incision-induced heat hyperalgesia", 35th Annual Meeting of Society for Neuroscience, Washington, United States. November 16, 2005.
Banik, R. K. "Potential drugs for postoperative pain and preemptive analgesia", Vertex Pharmaceuticals, San Diego, California, United States. October 14, 2005.
Banik, R. K., Subieta, A. R., Brennan, T. "Genetic and gender influence on pain sensitivity after pluntar incision", Society for Neuroscience, United States. January 01, 2005.
Banik, R. K., Wu, C., Brennan, T. "NGF expression in skin and DRG after plantar incision program", Society for Neuroscience, Washington DC, United States. January 01, 2005.
Banik, R. K., Katanosaka, K., Rocio, G., Higashi, T., Tominaga, M., Mizumura, K. "Bradykinin-induced physiological and behavioral responses of trpv1 deficient mice.", Society for Neuroscience, United States. January 01, 2004.
Banik, R. K., Brennan, T. "In vitro study of rat cutaneous nociceptor after incision", 33rd Annual Meeting of American Pain Society , Vancouver, Canada. January 01, 2004.
Banik, R. K., Subieta, A., Brennan, T. "Effects of anti-NGF treatment on C-fibers sensitized by plantar incision in vitro", Society for Neuroscience, United States. January 01, 2004.
Banik, R. K., Subieta, A., Brennan, T. "Anti-NGF treatment attenuates spontaneous pain and thermal, but not mechanical hyperalgesia, after hind paw incision", Society for Neuroscience, United States. January 01, 2003.
Banik, R. K., Kozaki, Y., Sato, J., Mizumura, K. "Adjuvant induced chronic inflammation causes increased bradykinin sensitivity of rat cutaneous C-fiber nociceptors and upregulation of B2 receptors in rat dorsal root ganglia", 10th World Congress of Pain , San Diego, California, United States. August 01, 2002.
Banik, R. K., Mizumura, K., Kasai, M., Kozaki, Y., Tamura, R., Sato, J. "Bradykinin sensitivity of nociceptors and nerve growth factor (NGF)", Japanese Journal of Physiology Supplement. January 01, 2001.
Banik, R. K. "Asian pain symposium", Increassed bradykinin sensitivity of cutaneous C-fiber nociceptors after chronic inflammation in the rats, Kyoto, Japan. December 01, 2000.
Banik, R. K. "Chronic inflammation induced modulation of the bradykinin response studied in vitro", 77th Annual meeting of Japanese Physiological Society, Keio University, Tokyo, Japan. March 29, 2000.
Banik, R. K., Kozaki, Y., Kasai, M., Andoh, T., Sato, J., Mizumura, K. "Increased bradykinin B2 receptor expression of adjuvant inflamed rats involved in the enhanced sensitivity of cutaneous nociceptors", Neuroscience research Supplement, United States. January 01, 2000.
Banik, R. K. "Increased responsiveness of C-fiber nociceptors to bradykinin and relative involvement of bradykinin B1 and B2 receptors in chronic inflammation", Annual Meeting of the Japanese Association for the Study of Pain, Tokyo, Japan. December 11, 1999.
Banik, R. K. "Strain differences in norepinephrine excitation of C-fiber nociceptors in Sprague-Dawley", 46th Annual Meeting of the Chubu Physiological Society, Nagoya City Medical School , Nagoya, Japan. October 16, 1999.
Banik, R. K., Mizumura, K., Sato, J., Kasai, M. "B2 receptor mediated bradykinin sensitivity of primary afferents re-examined role of NGF", Official Satellite Meeting of the 9th world Congress of pain , The Primary Nociceptive Neuron. January 01, 1999.
Banik, R. K., Sato, J., Yajima, H., Kumazawa, T., Mizumura, K. "Sympathetic modulation of cutaneous nociceptors", Japanese Journal of Physiology supplement . January 01, 1999.
Banik, R. K. "Norepinephrine induced facilitation of bradykinin response mediated", Summer Seminar , 2-AR, Gifu, Japan. August 26, 1998.
Banik, R. K., Sato, J., Mizumura, K. "2-adrenoceptor mediates norepinephrine-induced sensitization of the bradykinin response of cutaneous nociceptors in normal rats.", Society for Neuroscience abstract. January 01, 1998.
Banik, R. K., Kim, P. Y., Albritton, D., Huh, B. "Intravenous Ketamine Infusion for Refractory pain in Ambulatory Cancer Patients: Immediate but short lived relief", Chicago, Illinois, United States. January 01, 1925.
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Professional Memberships
American Society of Anesthesiologists
Minnesota Society of Anesthesiology
American Society of Regional Anesthesia & Pain Medicine
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Clinical Summary
Schedule an appointment with Dr. Banik at the Clinic for Comprehensive Pain Management by calling 612-673-5400.