Richard Bianco

Director of Experimental Surgery
Selected Publications

Selected Publications

Schappa Faustich, J., Lahti, M., Ashworth, P., Dalmasso, A. P., Moklyak, Y., Bianco, R. W., 2022. New Model for the Assessment of Transcatheter Aortic Valve Replacement Devices in Sheep. Journal Of Investigative Surgery , 35 (2): 371-377.
Kelly, R. F., Bianco, R. W., 2021. Increased utilization of bioprosthetic aortic valve technology: Trends, drivers, controversies and future directions. Expert Review of Cardiovascular Therapy , 19 (6): 537-546. Minneapolis, United States:
doi: PubMed ID: 33928833.
Lahti, M., Moklyak, Y., 2020. Anisotropic Polytetrafluoroethylene Cardiovascular Conduits Spontaneously Expand in a Growing Lamb Model. In Bianco, R. W. (Ed.), Journal Of Investigative Surgery , 1-7.
Hofferberth, S. C., Saeed, M. Y., Tomholt, L., Fernandes, M. C., Payne, C. J., Price, K., Marx, G. R., Esch, J. J., Brown, D. W., Brown, J., Hammer, P. E., Bianco, R. W., Weaver, J. C., Edelman, E. R., Del Nido, P. J., 2020. A geometrically adaptable heart valve replacement.. Science translational medicine, 12 (531):
Zhang, B. L., Bianco, R. W., Schoen, F. J., 2019. Preclinical Assessment of Cardiac Valve Substitutes: Current Status and Considerations for Engineered Tissue Heart Valves.. Frontiers in Cardiovascular Medicine, 6 72.
doi: PubMed ID: 31231661.
Koodie, L., Robertson, M. G., Chandrashekar, M., Ruth, G., Dunning, M., Bianco, R. W., Davydova, J., 2019. Rodents Versus Pig Model for Assessing the Performance of Serotype Chimeric Ad5/3 Oncolytic Adenoviruses.. Cancers, 11 (2):
doi: PubMed ID: 30744019.
Reimer, J., Lahti, M., Berry, J., Johnson, S., Bianco, R. W., Tranquillo, R. T., 2017. Corrigendum: Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs.. Nature communications, 8 14297.
doi: PubMed ID: 28094248.
Syedain, Z. H., Remer, J., Schmidt, J. B., Lahti, M., Berry, J., Bianco, R. W., Tranquillo, R. T., 2015. 6-Month Aortic Valve Implantation of an Off-The-Shelf Tissue-Engineered Valve in Sheep. Biomaterials, 73 175-184.
Schomburg, J., Medina, E., Lahti, M., Bianco, R. W., 2012. Dabigatran Versus Warfarin After Mechanical Mitral Valve Replacement in the Swine Model. Journal of Investigative Surgery , 25 (3): 150-155.
Schomburg, J., Lahti, M., Ruth, G. R., Bianco, R. W., 2011. Internal Aortic Annuloplasty: A Novel Technique. Journal of Investigative Surgery , 24 222-226.
Rivard, A. L., Suwan, P. T., Imaninaini, K., Gallegos, R. P., Bianco, R. W., 2007. Development of a Sheep Model of Atrial Fibrillation for Preclinical Prosthetic Valve Testing. The Journal of Heart Valve Disease , 16 314-323.
Young, J. D., Bianco, R. W., Fung, J. J., Lackner, A. A., 2006. Animal activism and intimidation of scientists. Science, 314 (5801): 923-924.
Gallegos, R. P., Rivard, A. L., Suwan, P. T., Black, S., Bertog, S., Steinseifer, U., Armien, A., Lahti, M., Bianco, R. W., 2006. In-Vivo Experience with the Triflo Trileaflet Mechanical Heart Valve. The Journal of Heart Valve Disease, 15 791-799.
Bianco, R. W., 2005. Re: Gregoric ID, Frazier OH, Tamez D, et al: Thrombogenicity of mechanical aortic valves in an animal model: site specific testing is crucial. ASAIO J 50: 376-380, 2004.. ASAIO journal (American Society for Artificial Internal Organs : 1992), 51 (1): 121; author reply 122.
Grehan, J. F., Casagrande, I., Oliveira, E. L., Santos, P. C., Pessa, C. J., Gerola, L. R., Buffolo, E., Mrachek, J., Norris, M. E., Lahti, M. T., Bianco, R. W., 2001. A juvenile sheep model for the long-term evaluation of stentless bioprostheses implanted as aortic root replacements.. The Journal of heart valve disease, 10 (4): 505-12.
PubMed ID: 11499598.
Westaby, S., Bianco, R. W., Katsumata, T., Termin, P., 1999. The Carbomedics "Oxford" Photofix stentless valve (PSV). Seminars in Thoracic and Cardiovascular Surgery , 11 (4 Suppl 1): 206-209.
Salerno, C. T., Pederson, T. S., Ouyang, D. W., Bolman, 3rd, R. M., Bianco, R. W., 1998. Chronic evaluation of orthotopically implanted bileaflet mechanical aortic valves in adult domestic sheep.. Journal of investigative surgery : the official journal of the Academy of Surgical Research, 11 (5): 341-7.
PubMed ID: 9827651.
Salerno, C. T., Droel, J., Bianco, R. W., 1998. Current state of in vivo preclinical heart valve evaluation. The Journal of Heart Valve Disease , 7 (2): 158-162.
Ouyang, D. W., Salerno, C. T., Pederson, T. S., Bolman III, R. M., Bianco, R. W., 1998. Long-Term Evaluation of Orthotopically Implanted Stentless Bioprosthetic Aortic Valves in Juvenile Sheep. Journal of Investigative Surgery , 11 175-183.
Bianco, R. W., 1997. Cardiovascular Implants Cardiac Valve Prostheses. ANSI/AAMI/ISO 5840:1996 Association for the Advancement of Medical Instrumentation,
Bianco, R. W., Grehan, J. F., Svendsen, C. A., 1997. Animal models in cardiovascular biomaterials testing . In Ratner, B., Hoffman, A., Schoen, F., Lemons, J. (Eds.), Biomaterials Science: An Introduction to Materials in Medicine Academic Press, San Diego, California,
Bianco, R. W., Phillips, R., Mrachek, J. P., Witson, J., 1996. Feasibility evaluation of a new pericardial bioprosthesis with dye mediated photo-oxidized bovine pericardial tissue . The Journal of Heart Valve Disease, 5 (3): 317-322.
Grants and Patents

Grants and Patents


Calcified Annulus Model for Transcatheter Aortic Valve Replacement.



MMC 220 Mayo
220 Delaware Street S.E.
Minneapolis, MN 55455

Administrative Contact

Steff Yorek |  612-625-4937 |