Silvia Mangia

Faculty, PhD Program in Medical Physics
Faculty, Graduate Program in Neuroscience


Dr. Mangia is a Professor in the Department of Radiology at the University of Minnesota. She got her master degree in Physics (1999), the Ph.D. in Biophysics (2003) and the title of "Specialist in Medical Physics" (2005) at the University of Rome "La Sapienza" (Italy). Since 2004 she has been working at the Center for Magnetic Resonance Research (CMRR).

Research Summary

Functional studies of human brain metabolism under increased or decreased neuronal activity
Neurovascular coupling and neuro-glia interactions
Oxidative and non-oxidative brain metabolism; glucose and lactate metabolism
Novel MR contrasts based on rotating frame relaxation measurements, magnetization transfer and chemical exchange
Applications of novel MRI/MRS protocols for studies of neurological diseases as Parkinson's disease, schizophrenia, multiple sclerosis Measurements of blood flow with arterial spin labeling methods, and their application to diseases as diabetes
Proton NMR Spectroscopy at high fields
Resting state fMRI, especially in relation to brain metabolism


PhD, University of Rome “La Sapienza”,
Major: Biophysics

Fellowships, Residencies, and Visiting Engagements

MRI/MRS, Fellowship
University of Minnesota Medical School
Minneapolils, Minnesota, United States

Professional Memberships

International Society for Cerebral Blood Flow and Metabolism
International Society of Magnetic Resonance in Medicine
American Diabetes Association



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