Stephen Huddleston, MD, PhD
Administrative Contact
Jenn Johnson | 612-625-8698 | [email protected]
Mailing Address
MMC 207, 420 Delaware St. SE
Minneapolis, MN 55455
Pronouns: he/him/his
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Biography
Dr. Huddleston joined the faculty at the University of Minnesota in December 2015 where he is an Associate Professor of Surgery in the Division of Cardiothoracic Surgery, and the Surgical Director of the Lung Transplant Program at the University of Minnesota Medical Center. He received his medical degree from Columbia University in 2000 and completed his internship and residency in General Surgery at the University of Minnesota. Dr. Huddleston received his Ph.D. in surgery at University of Minnesota in 2009 defending his thesis, “Graft Antigen-Specific CD4+ T cells require CD154 Expression to Clonally Expand and Differentiate to the Th1 phenotype and initiate mTOR Dependent Intimal Hyperplasia in Cardiac Allografts.” After completing his cardiothoracic surgery training at the Johns Hopkins Hospital in Baltimore, MD, he was a private practice cardiothoracic surgeon at St. Luke’s Hospital in Duluth, MN starting in 2012 until he returned to the University of Minnesota. He is board certified in Surgery and Thoracic Surgery.
Dr. Huddleston has mentored numerous medical students and residents with an interest in cardiac surgery, and he teaches cardiothoracic surgery fellows at the University of Minnesota Medical Center, St. John's Hospital and the Veterans Administration Medical Center-Minneapolis.
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Education
BA, University of Kansas, 1996
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Publications
1: Li R, Luo Q, Green D, Huddleston S. Smaller Hospital Size is Associated With Higher Mortality in Stanford Type A Aortic Dissection. Vasc Endovascular Surg. 2024 Aug 26:15385744241278839. doi: 10.1177/15385744241278839. Epub ahead of print. PMID: 39185819.
2: Li R, Huddleston SJ, Prastein DJ. In-hospital outcome of type A aortic dissection repair in patients with chronic obstructive pulmonary disease: A population study of National Inpatient Sample from 2015 to 2020. Cardiovasc Revasc Med. 2024 Jun 15:S1553-8389(24)00543-8. doi: 10.1016/j.carrev.2024.06.013. Epub ahead of print. PMID: 38890061.
3: Li R, Luo Q, Huddleston SJ. Patients with metastatic cancer have worse short-term coronary artery bypass grafting outcomes: A population-based study of National Inpatient Sample from 2015 to 2020. Cardiovasc Revasc Med. 2024 May 22:S1553-8389(24)00497-4. doi: 10.1016/j.carrev.2024.05.029. Epub ahead of print. PMID: 38796318.
4: Lanigan M, Siers D, Schramski M, Shaffer A, John R, Knoper R, Huddleston S, Gunn-Sandell L, Kaizer A, Perry TE. The Adherence to an Intraoperative Blood Product Transfusion Algorithm Is Associated With Reduced Blood Product Transfusions in Cardiac Surgical Patients Undergoing Coronary Artery Bypass Grafts and Aortic and/or Valve Replacement Surgery: A Single-Center, Observational Study. J Cardiothorac Vasc Anesth. 2024
May;38(5):1135-1143. doi: 10.1053/j.jvca.2024.01.029. Epub 2024 Feb 1. PMID: 38413344.
5: Li R, Luo Q, Huddleston SJ. African Americans have worse outcomes after transcatheter and surgical aortic valve replacement: A national inpatient sample analysis from 2015 to 2020. J Cardiol. 2024 Aug;84(2):105-112. doi: 10.1016/j.jjcc.2024.02.003. Epub 2024 Feb 17. PMID: 38373538.
6: Li R, Luo Q, Yanavitski M, Huddleston SJ. Smoker's paradox in transcatheter aortic valve replacement: A National Inpatient Sample analysis from 2015 to 2020. Cardiovasc Revasc Med. 2024 May;62:21-26. doi: 10.1016/j.carrev.2023.11.021. Epub 2023 Nov 30. PMID: 38052714.
7: Li R, Huddleston S. Development of Comorbidity Index for in-hospital mortality for patients who underwent coronary artery
revascularization. J Cardiovasc Surg (Torino). 2023 Dec;64(6):678-685. doi: 10.23736/S0021-9509.23.12833-3. Epub 2023 Nov 21. PMID: 37987738.
8: Li R, Luo Q, Green D, Huddleston SJ. Weekend Admission is Associated with Higher Kidney Failures after Thoracic Endovascular Aneurysm Repair for Stanford Type B Aortic Dissection. Vasc Endovascular Surg. 2024 Apr;58(4):372-381. doi: 10.1177/15385744231217622. Epub 2023 Nov 18. PMID: 37978945.
9: Salami AC, Huddleston SJ. Beating the odds: long-term survival after lung transplantation. J Thorac Dis. 2023 Sep 28;15(9):4558-4560. doi: 10.21037/jtd-23-1018. Epub 2023 Sep 11. PMID: 37868854; PMCID: PMC10586948.
10: Aggarwal R, Potel KN, Jackson S, Lemke NT, Kelly RF, Soule M, Diaz-Gutierrez I, Shumway SJ, Patil J, Hertz M, Nijjar PS, Huddleston SJ. Impact of lung transplantation on diastolic dysfunction in recipients with pretransplant pulmonary hypertension. J Thorac Cardiovasc Surg. 2024 May;167(5):1643-1653.e2. doi: 10.1016/j.jtcvs.2023.09.031. Epub 2023 Sep 21. PMID: 37741317.
11: Li R, Luo Q, Yanavitski M, Huddleston SJ. Disparity among Asian Americans in transcatheter and surgical aortic valve replacement. Cardiovasc Revasc Med. 2024 Feb;59:84-90. doi: 10.1016/j.carrev.2023.08.016. Epub 2023 Sep 1. PMID:37673721.
12: Kazmirczak F, Prisco SZ, Knoper R, Huddleston S, Raveendran G, Pritzker M, Thenappan T, Prins KW, Gurevich S. Effect of Combination of Balloon Pulmonary Angioplasty and Medical Therapy on Reverse Right Ventricular Remodeling and Hemodynamics in Chronic Thromboembolic Pulmonary Hypertension. J Invasive Cardiol. 2023 Jun;35(6):E312-E320. doi: 10.25270/jic/23.00060. PMID: 37410748; PMCID: PMC10428086.
13: Siddique A, Parekh KR, Huddleston SJ, Shults A, Locke JE, Keshavamurthy S, Schwartz G, Hartwig MG, Whitson BA. A call to action in thoracic transplant surgical training. J Heart Lung Transplant. 2023 Nov;42(11):1627-1631. doi: 10.1016/j.healun.2023.05.017. Epub 2023 Jun 1. PMID: 37268052.
14: Hingtgen A, Siems C, Huddleston SJ, John R. Posterolateral thoracotomy: unique approach to tricuspid valve replacement after right pneumonectomy. J Surg Case Rep. 2023 Apr 18;2023(4):rjad186. doi: 10.1093/jscr/rjad186. PMID: 37082650; PMCID: PMC10112948.
15: Subramaniam K, Loor G, Chan EG, Bottiger BA, Ius F, Hartwig MG, Daoud D, Zhang Q, Wei Q, Villavicencio-Theoduloz MA, Osho AA, Chandrashekaran S, Noguchi Machuca T, Van Raemdonck D, Neyrinck A, Toyoda Y, Kashem MA, Huddleston S, Ryssel NR, Sanchez PG. Intraoperative Red Blood Cell Transfusion and Primary Graft Dysfunction After Lung Transplantation. Transplantation. 2023 Jul1;107(7):1573-1579. doi: 10.1097/TP.0000000000004545. Epub 2023 Mar 24. PMID: 36959119.
16: Doenges JE, Reed AB, Huddleston S, Wang Q, Valentine RJ. Persistent malperfusion after central aortic repair in acute type I aortic dissections. J
Vasc Surg. 2023 Jun;77(6):1618-1624. doi: 10.1016/j.jvs.2023.02.004. Epub 2023 Feb 14. PMID: 36796591.
17: Aggarwal R, Jackson S, Lemke NT, Trager L, Shumway SJ, Kelly RF, Hertz M, Huddleston SJ. Time since primary transplant and poor functional status predict survival after redo lung transplant. J Thorac Dis. 2022 Oct;14(10):3819-3830. doi: 10.21037/jtd-22-334. PMID: 36389317; PMCID: PMC9641320.
18: Huddleston SJ, Kelly RF. Commentary: Beating the odds: Success in extramural funding renewal. JTCVS Open. 2022 Feb 14;9:176-177. doi: 10.1016/j.xjon.2021.11.013. PMID: 36003422; PMCID: PMC9390177.
19: Diaz-Gutierrez I, Huddleston SJ. Editorial: Discerning the role of diaphragm application in lung transplantation. Clin Transplant. 2022 Jul;36(7):e14712. doi: 10.1111/ctr.14712. Epub 2022 May 23. PMID: 35580178.
20: Lanigan M, Siers D, Wilkey A, Barakat A, Shaffer A, John R, Knoper R, Huddleston S, Kaizer A, Perry TE. The Use of a Viscoelastic-Based
Transfusion Algorithm Significantly Reduces Non-red Blood Cell Transfusion in Patients Undergoing Left Ventricular Assist Device Placement or Heart
Transplantation: A Single-Center Observational Study. J Cardiothorac Vasc Anesth. 2022 Aug;36(8 Pt B):3038-3046. doi: 10.1053/j.jvca.2022.03.017. Epub 2022 Mar 22. PMID: 35545456.
21: Loor G, Huddleston S, Hartwig M, Bottiger B, Daoud D, Wei Q, Zhang Q, Ius F, Warnecke G, Villavicencio MA, Tirabassi B, Machuca TN, Van Raemdonck D, Frick AE, Neyrinck A, Toyoda Y, Kashem MA, Landeweer M, Chandrashekaran S. Effect of mode of intraoperative support on primary graft dysfunction after lung transplant. J Thorac Cardiovasc Surg. 2022 Nov;164(5):1351-1361.e4. doi: 10.1016/j.jtcvs.2021.10.076. Epub 2022 Feb 4. PMID: 35236625.
22: Siems C, Huddleston S, John R. A Brief History of Xenotransplantation. Ann Thorac Surg. 2022 Mar;113(3):706-710. doi: 10.1016/j.athoracsur.2022.01.005. PMID: 35168782.
23: Aggarwal R, Jackson S, Lemke NT, Shumway SJ, Kelly RF, Hertz M, Huddleston SJ. Lung Transplant Recipients With Prior Coronary Artery Bypass Grafting Are at Increased Risk of Death and Early Perioperative Hemorrhage. Semin Thorac Cardiovasc Surg. 2022 Summer;34(2):763-770. doi: 10.1053/j.semtcvs.2021.03.048. Epub 2021 May 21. PMID: 34023526.
24: Huddleston SJ, Kelly RF. Commentary: Del Nido cardioplegia with a "hot shot". J Thorac Cardiovasc Surg. 2022 Oct;164(4):e158-e159. doi: 10.1016/j.jtcvs.2020.12.066. Epub 2020 Dec 25. PMID: 33485661.
25: Huddleston SJ, Kelly RF. The Time for Change Is Now. Ann Thorac Surg. 2021 Sep;112(3):735-736. doi: 10.1016/j.athoracsur.2020.10.041. Epub 2020 Dec 3. PMID: 33279537.
26: Huddleston SJ, Shumway SJ. Minimally Invasive Left Atrial Appendage Excision and Atrial Fibrillation Ablation as Secondary Prevention of
Thromboembolic Stroke-Weighing the Risk Versus the Benefit. Semin Thorac Cardiovasc Surg. 2021 Spring;33(1):68-69. doi: 10.1053/j.semtcvs.2020.09.014. Epub 2020 Sep 20. PMID: 32966887.
27: Huddleston SJ, Kelly RF. Commentary: Coronary revascularization in patients with left ventricular systolic dysfunction. J Thorac Cardiovasc Surg.
2021 Mar;161(3):1033-1034. doi: 10.1016/j.jtcvs.2020.07.048. Epub 2020 Jul 18. PMID: 32778463.
28: Huddleston SJ, Jackson S, Kane K, Lemke N, Shaffer AW, Soule M, Hertz M, Shumway S, Qi S, Perry T, Kelly R. Separate Effect of Perioperative Recombinant Human Factor VIIa Administration and Packed Red Blood Cell Transfusions on Midterm Survival in Lung Transplantation Recipients. J Cardiothorac Vasc Anesth. 2020 Nov;34(11):3013-3020. doi: 10.1053/j.jvca.2020.05.038. Epub 2020 Jun 3. PMID: 32718888.
29: Spratt JR, Mattison LM, Kerns NK, Huddleston SJ, Meyer L, Iles TL, Loor G, Iaizzo PA. Prolonged extracorporeal preservation and evaluation of human lungs with portable normothermic ex vivo perfusion. Clin Transplant. 2020 Mar;34(3):e13801. doi: 10.1111/ctr.13801. Epub 2020 Feb 19. PMID:
31999865.
30: Huddleston SJ, Brown R, Rudser K, Goswami U, Tomic R, Lemke NT, Shaffer AW, Soule M, Hertz M, Shumway S, Kelly R, Loor G. Need for tracheostomy after lung transplant predicts decreased mid- and long-term survival. Clin Transplant. 2020 Jan;34(1):e13766. doi: 10.1111/ctr.13766. Epub 2019 Dec 31. PMID: 31815320.
31: Loor G, Warnecke G, Villavicencio MA, Smith MA, Kukreja J, Ardehali A, Hartwig M, Daneshmand MA, Hertz MI, Huddleston S, Haverich A, Madsen
JC, Van Raemdonck D. Portable normothermic ex-vivo lung perfusion, ventilation, and functional assessment with the Organ Care System on donor lung use for transplantation from extended-criteria donors (EXPAND): a single-arm, pivotal trial. Lancet Respir Med. 2019 Nov;7(11):975-984. doi: 10.1016/S2213-2600(19)30200-0. Epub 2019 Aug 1. PMID: 31378427.
32: Elde S, Huddleston S, Jackson S, Kelly R, Shumway S, Loor G. Tailored Approach to Surgical Exposure Reduces Surgical Site Complications after
Bilateral Lung Transplantation. Surg Infect (Larchmt). 2017 Nov/Dec;18(8):929-935. doi: 10.1089/sur.2017.144. Epub 2017 Oct 20. PMID: 29053438.
33: Huddleston SJ, Shumway S. Great Institutions in Cardiothoracic Surgery: The University of Minnesota. Semin Thorac Cardiovasc Surg. 2016
Autumn;28(3):712-718. doi: 10.1053/j.semtcvs.2016.09.002. Epub 2016 Oct 29. PMID: 28285678.
34: Mullenix PS, Huddleston SJ, Stojadinovic A, Trachiotis GD, Alexander EP. A new heart: somatic stem cells and myocardial regeneration. J Surg Oncol. 2012 Apr 1;105(5):475-80. doi: 10.1002/jso.23014. PMID: 22441899.
35: Huddleston SJ, Wei Lum Y, Black JH 3rd, Meneshian A. Image of the month. Pulmonary artery pseudoaneurysm. Arch Surg. 2011 Nov;146(11):1331-2. doi: 10.1001/archsurg.2011.283-a. PMID: 22106329.
36: Rueth NM, Murray SE, Huddleston SJ, Abbott AM, Greeno EW, Kirstein MN, Tuttle TM. Severe electrolyte disturbances after hyperthermic intraperitoneal chemotherapy: oxaliplatin versus mitomycin C. Ann Surg Oncol. 2011 Jan;18(1):174-80. doi: 10.1245/s10434-010-1210-1. Epub 2010 Jul 8. PMID: 20614192.
37: Shaw D, Huddleston S, Beilman G. Anterograde intussusception following laparoscopic Roux-en-Y gastric bypass: a case report and review of the literature. Obes Surg. 2010 Aug;20(8):1191-4. doi: 10.1007/ s11695-009-0037-y. Epub 2009 Dec 18. PMID: 20020221.
38: Whitson BA, Huddleston SJ, Savik K, Shumway SJ. Risk of adverse outcomes associated with blood transfusion after cardiac surgery depends on the amount of transfusion. J Surg Res. 2010 Jan;158(1):20-7. doi: 10.1016/j.jss.2008.10.015. PMID: 19181341.
39: Kang J, Huddleston SJ, Fraser JM, Khoruts A. De novo induction of antigen-specific CD4+CD25+Foxp3+ regulatory T cells in vivo following systemic antigen administration accompanied by blockade of mTOR. J Leukoc Biol. 2008 May;83(5):1230-9. doi: 10.1189/jlb.1207851. Epub 2008 Feb 12. PMID: 18270248.
40: Whitson BA, Huddleston SJ, Savik K, Shumway SJ. Bloodless cardiac surgery is associated with decreased morbidity and mortality. J Card Surg. 2007 Sep-Oct;22(5):373-8. doi: 10.1111/j.1540-8191.2007.00428.x. PMID: 17803571.
41: John R, Lietz K, Huddleston S, Matas A, Liao K, Shumway S, Joyce L, Bolman RM. Perioperative outcomes of cardiac surgery in kidney and kidney-
pancreastransplant recipients. J Thorac Cardiovasc Surg. 2007 May;133(5):1212-9. doi: 10.1016/j.jtcvs.2006.11.041. Epub 2007 Mar 28. PMID: 17467431.
42: Whitson BA, Barnett SJ, Huddleston SJ, Mohr WJ. Pulmonary embolism associated with a vacuum-induced arm compartment syndrome: a setting for increased vigilance. J Burn Care Res. 2006 Jul-Aug;27(4):552-4. doi:10.1097/01.BCR.0000225914.33926.4C. PMID: 16819365.
43: Huddleston SJ, Hays WS, Filatenkov A, Ingulli E, Jenkins MK. CD154+ graft antigen-specific CD4+ T cells are sufficient for chronic rejection of minor antigen incompatible heart grafts. Am J Transplant. 2006 Jun;6(6):1312-9. doi: 10.1111/j.1600-6143.2006.01309.x. PMID: 16686755.
44: Koticha DK, Huddleston SJ, Witkin JW, Baldini G. Role of the cysteine-rich domain of the t-SNARE component, SYNDET, in membrane binding and subcellular localization. J Biol Chem. 1999 Mar 26;274(13):9053-60. doi: 10.1074/jbc.274.13.9053. PMID: 10085154.
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Research
Dr. Huddleston's primary academic interest is in lung transplantation with a focus on clinical outcomes and transplant immunology, as well as ex vivo lung perfusion. He has been the site principal investigator for two multicenter clinical trials examining the role of warm ex vivo lung perfusion in lung transplant. The device used for this research, TransMedics Lung OCS, is now FDA approved and expanding the donor pool. Also, he collaborates with Regents Professor Marc Jenkins, PhD, an immunologist using advanced immunologic techniques to detect and characterize CD4+ T cells with specificity for the donor lung in the blood of lung transplant recipients. In addition to transplant immunology, he has an interest in lung transplant and cardiac surgery outcomes research using institutional and national databases to inform clinical decision making and improve outcomes.
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Licensures & Certifications
American Board of Thoracic Surgery 2013 - Present
Minnesota Medical License (#46209) 2012 - Present
American Board of Surgery 2009 - Present
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Awards, Honors and Recognitions
Cassius Ellis Award, University of Minnesota, 2009
The Doctor David Gaviser Mount Sinai Surgical Research Award, University of Minnesota, 2008
Resident Award for Basic Research, Minnesota Surgical Society, 2004
Richard C. Lillehei, MD/Earl Bakken Prize, University of Minnesota, 2004
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Presentations
Huddleston, S. J. "Detection of Directly Alloreactive Graft Antigen-Specific CD4+ T Cells in Peripheral Blood", ISHLT 42nd Annual Meeting & Scientific Sessions, Boston, Massachusetts. April 28, 2022.
Ius, F., Van Raemdonck, D., Hartwig, M., Bottiger, B., Loor, G., Daoud, D., Wei, Q., Villavicencio, M., Osho, A., Chandrashekaran, S., Machuca, T., Neyrinck, A., Toyoda, Y., Kashem, M., Huddleston, S. J., Myers, M., Sanchez, P., Ryssel, N., Warnecke, G. "Effect of Surgical Exposure on Outcomes in Lung Transplantation: Insight from the International Multicenter Extracorporeal Life Support (ECLS) in Lung Transplantation Registry", ISHLT 41st Annual Meeting & Scientific Sessions – Virtual Experience, Minneapolis, Minnesota. April 28, 2021.
Villavicencio, M., Kashem, M., Loor, G., Hartwig, M., Bottiger, B., Ius, F., Daoud, D., Warnecke, G., Wei, Q., Chandrashekaran, S., Machuca, T., Van Raemdonck, D., Neyrinck, A., Huddleston, S. J., Myers, M., Moonsamy, P., Toyoda, Y. "Impact of Cold Ischemic Time on Morbidity and Mortality after Lung Transplantation. An Updated Analysis of the International Multicenter Extracorporeal Life Support in Lung Transplantation Registry", ISHLT 41st Annual Meeting & Scientific Sessions – Virtual Experience, Minneapolis, Minnesota. April 25, 2021.
Richardson, S., Olejniczack, M., Jackson, S., Siers, D., Huddleston, S. J. "Predictors of Primary Graft Dysfunction Following Bilateral Lung Transplantation", ISHLT 41st Annual Meeting & Scientific Sessions – Virtual Experience, Minneapolis, Minnesota. April 25, 2021.
Aggarwal, R., Jackson, S., Lemke, N., Huddleston, S. J. "Time from Start of Agonal Phase to Pulmonary Artery Cross Clamp in Donor Cardiac Death Donors Does Not Correlate with Diminished Recipient Lung Function or Survival", ISHLT 41st Annual Meeting & Scientific Sessions – Virtual Experience, Minneapolis, Minnesota. April 25, 2021.
Kashem, M., Loor, G., Hartwig, M., Villavicencio, M., Axtell, A., Sanchez, P., Ryssel, N., Bottiger, B., Daoud, D., Zhao, H., Wei, Q., Bussetty, A., Ius, F., Warnecke, G., Machuca, T., Van Raemdonck, D., Frick, A., Neyrinck, A., Chandrashekaran, S., Toyoda, Y., Huddleston, S. J. "Interim Results - The Effect of Donor Type (Donor after Cardiac Death vs Donor after Brain Death) and Use of Intraoperative Extracorporeal Lung Support on Survival after Lung Transplantation", ISHLT 41st Annual Meeting & Scientific Sessions – Virtual Experience, Minneapolis, Minnesota. April 25, 2021.
Huddlestson, S. J. "When to Use Nitric Oxide of Flolan or both?", Symposium of perioperative right heart failure in the cardiac surgical patient, Department of Anesthesiology, Minneapolis, Minnesota, United States. March 13, 2021.
Huddlestson, S. J. "Mitral Regurgitation: Curing the Disease", Lillehei Symposium, MHealth Fairview, Minneapolis, Minnesota, United States. September 20, 2020.
Huddlestson, S. J. "Current status of Ex vivo lung perfusion in lung transplantation", 21st Annual Cutting Edge Conference (Virtual), MHealth Fairview, Minneapolis, Minnesota, United States. March 09, 2020.
Huddlestson, S. J. "Tracking Graft Antigen-Specific CD4+ T cells in Lung Transplant Recipients Using Peptide:HLA Tetramers", Research-in-Progress Conference, Division of Pulmonary & Critical Care Medicine at Northwestern, Chicago, Illinois, United States. March 09, 2020.
Huddlestson, S. J. "Immune System, Tolerance and Reject", 20th Annual Cutting Edge Conference: Two Decades of Progress in Transplantation, MHealth Fairview, Minneapolis, Minnesota, United States. April 11, 2019.
Huddleston, S. J. "Modified Bypass Strategy for Lung Transplant, The Extracorporeal Life Support in Lung Transplantation Committee", 39th Annual Conference of the International Society for Heart & Lung Transplantation, Orlando, Florida, United States. April 02, 2019.
Huddlestson, S. J. "The Evolving Role of Organ Care Systems in Lung Transplantation", Earl E. Bakken Surgical Device Symposium 2018, MHealth Fairview, Minneapolis, Minnesota, United States. October 12, 2018.
Huddleston, S. J. " ", International Transplant Nurses Society (ITNS) Dinner, Minneapolis, Minnesota, United States. April 01, 2018.
Huddlestson, S. J. "Lung transplant at the University of Minnesota", Sanford Bemidji, MHealth Fairview / Sanford, Minneapolis, Minnesota, United States. November 30, 2017.
Huddleston, S. J. "Tracheostomy after lung transplant predicts mid and long term decreased survival.", 37th Annual Meeting, The International Society for Heart & Lung Transplantation, San Diego, California, United States. April 01, 2017.
Huddleston, S. J., (Author), Shumway, S. J., (Author) "Great Institutions in Cardiothroacic Surgery: The University of Minnesota", Lillehei Surgical Society, University of Minnesota, Houston, Texas, United States. January 01, 2017.
Huddleston, S. J. "The history of cardiac surgery at the University of Minnesota: How do we carry the tradition forward?", 31st Annual Meeting, The C Walton and Richard C Lillehei Surgical Society, Houston, Texas, United States. January 01, 2017.
Huddleston, S. J., Ingulli, E., Jenkins, M. K. "Delayed gratification: a program of intimal hyperplasia progresses even as graft antigen-specific CD4+ T cells subside", ACS Surgical Forum, New Orleans, Louisiana, United States. October 01, 2007.
Huddleston, S. J., Ingulli, E., Jenkins, M. K. "IFN-γ production by graft antigen-specific CD4+ T cells is not required for the development of intimal hyperplasia", 39th Annual Conference of the International Society for Heart and Lung Transplantation, San Francisco, California, United States. April 01, 2007.
Huddleston, S. J., Ingulli, E. "Rosiglitazone prevents intimal hyperplasia in a murine model of chronic rejection", World Transplant Congress, Boston, Massachusetts, United States. July 01, 2006.
Huddleston, S. J., Hays, W. S., Filatenkov, A., Ingulli, E., Jenkins, M. K. "Intragraft antigen-specific CD4+ T cell-mediated smoldering rejection associated with IFN-γ production", American Transplant Congress, Seattle, Washington, United States. May 01, 2005.
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Professional Memberships
Fellow (FACS), American College of Surgeons (ACS): October 27, 2019 - Present
Thoracic Organ Transplantation Committee, American Society of Transplant Surgeons (ASTS): 2019 - Present
International Society for Heart & Lung Transplantation: 2015 - Present
Society of Thoracic Surgeons: 2012 - Present
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Clinical Summary
In addition to coronary revascularization, valve repair and replacement, and aortic surgery, he performs lung transplant surgery. He is also Director of Aortic Surgery and performs complex redo surgery including redo aortic surgery on the aortic root, aortic arch and thoracoabdominal aorta.