Cyrus Jahansouz, MD

Assistant Professor,

Cyrus Jahansouz

Contact Info

Office Phone 612-899-2176

Office Address:
Colon and Rectal Surgery
420 Delaware Street SE, MMC 450
Minneapolis, MN 55455

Administrative Assistant Name
Alexandra Broek

Administrative Phone

Administrative Email

Additional Locations

Colon & Rectal Clinic:


Endoscopy Scheduling:


Administrative Phone:


Administrative Fax:


Assistant Professor

Medical School: University of Virginia

Residency: University of Minnesota

Fellowship: Cleveland Clinic Florida, Colon and Rectal Surgery


Awards & Recognition


  • 2017 Richard Lillehei/Earl Bakken Award in Experimental Research. Awarded by Lillehei Society, January 24, 2017.
  • 2017 University of Minnesota Department of Surgery Annual Poster Session, 1st Place.
  • “Excellence in Research Award” by American College of Surgeons for the category of “Bariatric Surgery/Foregut,” presented at American College of Surgeons, October 2017.
  • 2018 Henry Buchwald Award. Awarded to the surgical resident entering the senior year of residency training who has demonstrated the character, integrity, capability and performance to become an academic surgeon of the highest caliber.
  • 2019 David Gaviser Award. This award honors a resident each spring for outstanding achievement in surgical research. It is in memoriam of Dr. David Gaviser, a longtime clinical professor in the Department of Surgery who was the director of surgical education at Mount Sinai Hospital.


Research Summary/Interests


  • Gut Microbiome
  • Obesity
  • Colon and Rectal Cancer
  • Diverticulitis
  • Inflammatory Bowel Disease

My goal is to improve patients' outcomes following colorectal surgery by modifying and reconstituting the composition of the intestinal microbiome. We have only recently realized the potential for the microbiome to serve as a modifiable therapeutic target. I work in collaboration with my PhD partner, Dr. Christopher Staley, who has established a human-microbiota-associated (HMA) mouse model that allows stable engraftment of human intestinal microbiota into antibiotic-treated mice. Our research will humanize mice with the microbiota from patients with different gut microbial compositions and use our established colonic surgery murine model to evaluate the impact of these compositions on post-surgical complications, primarily in the healing of the colonic anastomosis.