Paul A. Iaizzo, PhD

Professor, Visible Heart Laboratories

Paul A. Iaizzo

Contact Info

Office Phone 612-624-7912

Fax 612-624-2002

Office Address:
B172 Mayo, MMC 195
420 Delaware Street S.E.
Minneapolis, MN 55455

Fellowship, Postdoctoral NIH research Department of Pharmacology, Mayo Foundation, Rochester MN; Postdoctoral Alexander von Humboldt-Stiftung Research, Department of Neurology, Technical University of Munich, Germany

PhD, University of Minnesota, Physiology (Neurophysiology)

M.S., Physiology, University of Minnesota, Duluth

B.S., Biology, University of Minnesota, Duluth

Post-doc, Pharmacology, Mayo Clinic (NIH fellowship)

Post-doc, Neurophysiology, Technical University of Munich



Research Summary/Interests

  • Translational Systems Physiology
  • Physiology of skeletal and cardiac muscle (in vivo, in situ and in vitro); Medical device design.
  • Cardiac Anatomy:
  • Pathophysiology of human skeletal muscle. Effects of anesthetic agents on the function of extrafusal and intrafusal skeletal muscle and cardiac muscle.
  • Development of novel instrumentation and biomedical devices for physiological monitoring, clinical evaluation and/or therapeutic use.
  • Role of elevated intracellular [Ca2+] in: 1) cell signaling; 2) dystrophic processes within skeletal muscle; and 3) cell toxicity.
  • Physiological and pathological oscillations of the musculoskeletal system (e.g., tremor, shiver and clonus).
  • Physiology of thermoregulation and biomedical applications of heat transfer in humans.
  • Non-invasive and invasive correlates of wound formation, status, healing and prevention: development of animal models, and the design of biomedical instrumentation.
  • Cervical and lumbar spinal cord biomechanics and management of back pain.