Tinen Iles

Assistant Professor Surgery
Biography

Research Summary

-Cardiac anatomy and physiology-Computational Simulation and Modeling for surgical planning, teaching and visualization-Device design and testing- bench testing and Visible Heart Methodologies -Hibernation physiology and translational applications of biomimicry - Ex Vivo Perfusion and pharmacologic pre/post-treatment for cardiothoracic surgery and transplantation

Education

PhD, University of Minnesota, Twin Cities
Major: Bioinformatics and Computational Biology
MS, University of Minnesota, Twin Cities
Major: Biological Sciences
BA/BS, Bethel University
Major: Biology

Media Appearances

VR and 3D printing for heart treatment: a tour, Alliance of Advanced Biomedical Engineering
2017
Bear Week: Scientist look to unlock mysteries of hibernation
2017
Bear study teams DNR, Medtronic and University of Minnesota researchers, Grand Forks Herald
2015
From the lab to the north woods , University of Minnesota Foundation
2015

Professional Memberships

Malignant Hyperthermia Association of the United States
International Society for Heart and Lung Transplantation
International Bear Association
Heart Rhythm Society
American Physiological Society
American Heart Association
Selected Presentations

Selected Presentations

Sacco, F., Paun, B., Lehmkuhl, O., Iles, T. L., Iaizzo, P. A., Houzeaux, G., Vásquez, M., Butakoff, C., Aguado-Sierra, J. "Electrophysiology Simulations of Female and Male Human Ventricles: Influence of Gender Phenotype and Endocardial Anatomy on Signal Propagation, The Heart by Numbers: Integrating Theory, Computation, and Experiment to Advance Cardiology ", Berlin, Germany. September 04, 2018.
Iles, T. L. "Bears and Cardiology ", Inspire Conference, Institute for Engineering in Medicine, September 01, 2018.
Iles, T. L., Laske, T. G., Garshelis, D. L., Mattison, L., Lee, B., Eisele, V., Gaasedelen, E., Iaizzo, P. A. "Medtronic Reveal LINQ™ Devices Provide Better Understanding of Hibernation Physiology in the American Black Bear (Ursus americanus)", Technical Brief, Journal of Medical Devices , April 01, 2017.
Bandschapp, O., Gonzalez, A., Iles, T. L., Mattison, L., Schmidt, M., Soule, C. L., Iaizzo, P. A. "Influence of Prior Statin Intake on Masseter Muscle Force During an Induced Malignant Hyperthermia Episode in Swine ", American Society of Anethesiologists Annual Meeting, January 01, 2016.
Iles, T. L., Howard, B., Garshelis, D., Laske, T. G., Mattison, L., Iaizzo, P. A. "3D Reconstruction of Black Bears: From Cubs to the World's Oldest Known Bear", Materialise Conference, January 01, 2016.
Spratt, J. R., Mattison, L. M., Iaizzo, P. A., Aldrich, N. K., Meyer, L., Iles, T. L., Kerwin, S., Simmones, B., Rogers, M., Loor, G. "Prolonged Extracorporeal Preservation and Evaluation of Human Lungs Initially Declined for Transplantation: A New Paradigm in Donor Evaluation ", American Association for Thoracic Surgery , January 01, 2016.
Howard, B. T., Iaizzo, P. A., Iles, T. L., Mattison, L., Meyers, P., Day, T., Kelly , R., Loor , G. "Prolonged Lung Preservation at 24 hours Using Donor Whole Blood Transfusion in the Organ Care System (OCS)", International Society for Heart and Lung Transplant , January 01, 2015.
Iles, T. L., Fuher, A., Thurk, S., Iaizzo , P. A. "Case Study: 3D Modeling and Visualization of a Patient with 28 Coronary Artery Stents and Triple Artery Bypass Graft ", Institute for Engineering in Medicine Conference, January 01, 2015.
Panoskaltsis-Mortari, A., Howard, B. T., Price, A., Ehrhardt, M., Iles, T. L., Meyer, C., Iaizzo , P. A., Loor , G. "A New Ex Vivo Model of ARDS Associated with Processed Blood Cell Transfusions", Abstract American Thoracic Society , January 01, 2015.
Iles, T. L., Howard, B. T., MacIver, R., St. Louis, J., Ameduri, R., Iaizzo , P. A. "Imaging, Modeling and Preservation of Hearts with Congenital Defects ", Imaging in Cardiovascular Interventions (ICI), Frankfurt, Germany. January 01, 2014.
Schmidt, M., Iles, T. L., Fernandaz, G., Benscoter, M., Franz, M., Iaizzo , P. A. "The Recording of Monophasic Action Potentials Simultaneously from both the Epicardial and Endocardial Surfaces of Porcine Hearts ", TCT, January 01, 2014.
Iles, T. L., Howard, B. T., MacIver, R., St. Louis, J., Ameduri, R., Iaizzo , P. A. "Imaging, Modeling and Preservation of Hearts with Congenital Defects ", Imaging in Cardiovascular Interventions, Congenital & Structural Interventions, Frankfurt, Germany. January 01, 2014.
Iles, T. L. "Hibernation Physiology and Cardiac Anatomy, Physiology and Devices ", STEM Honors Class Lectures, Burnsville School Systems, January 01, 2011.
Healy, T. L., Nelson, E., Pook, L., Gottshall , S. L. "Characterization of a Back Incision Model of Post-Surgical Pain in the Rat Using a Diode Laser ", Society for Neuroscience, January 01, 2010.
Healy, T. L., Schaeffer, C., Gottshall , S. L. "Characterization of a Model Ultraviolet B Irradiation in the Rat", Society for Neuroscience, January 01, 2009.
Marker, C. L., Healy, T. L., Gottshall , S. L. "Measuring Primary Mechanical Hyperalgesia in a Model of Osteoarthritis Pain in the Rat", Society for Neuroscience, January 01, 2008.
Healy, T. L., Marker, C. L., Gottshall , S. L. "Measuring Primary Mechanical Hyperalgesia in a Model of Adjuvant-Induced Chronic Joint Pain in the Rat ", Society for Neuroscience, January 01, 2008.