Aubie Shaw
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Credentials
PhD
Research Summary
Research in the Shaw lab focuses on the interaction between three cell types in the tumor microenvironment (carcinoma cells, fibroblasts and myeloid cells) in mediating tumor metastasis. Our research has shown that secreted factors from myeloid cells encourage the invasion of fibroblasts (leader fibroblasts); and this directly increases carcinoma cell invasion. Although we have identified some proteins that mediate this activity, our current work is examining the roles of RNAs in exosomes. Our work uses live cell microscopy to image cells in 3-dimensional constructs. Our current work uses CellMate3DTM, a chemically-defined tissue-like microenvironment composed of hyaluronic acid and chitosan (BRTI Life Sciences). BRTI Life Sciences is a local biotech company located in Two Harbors, MN and I work closely with BRTI researchers to develop novel therapeutics and cultivate local industry.
Service Summary
Area Editor
National Board of Medical Examiners, approximately 65 hours spent per year. (November 2019 - Present).
Review questions for the NBME Physiology Exam
Grant Reviewer
Department of Defense Breast Cancer Research Program, United States, approximately 130 hours spent per year. (December 2018 - Present).
Service to the University of Minnesota
Member, Clinical Competency Committee #3, approximately 48 hours spent per year. (May 23, 2022 - Present).
Member, Medical School Scholastic Standing Committee, approximately 15 hours spent per year. (November 29, 2021 - Present).
Overview Committee created to oversee COSSS (TC) and SSC (DU).
Member, Duluth Scientific Foundations Committee, approximately 30 hours spent per year. (2021 - Present).
Department
Member, Biomedical Sciences Curriculum Committee, approximately 30 hours spent per year. (October 10, 2018 - Present).
Education
Fellowships, Residencies, and Visiting Engagements
Honors and Recognition
Contact
Address
Department of Biomedical Sciences207 SMED
1035 University Drive
Duluth, MN 55812