C. Sophia Albott
,

Credentials

MD, MA

Head of the Division of Adult Mental Health (AMH), Assistant Professor

Biography

Bio

I received a BA in Neuroscience from Grinnell College in Iowa and then graduated with a BA and a Master in Philosophy from the Catholic University of Leuven in Belgium. I completed medical school here at the University of Minnesota, where I also did my residency in psychiatry and my T32 postdoctoral fellowship in psychiatric comorbidity. I am an adult psychiatrist with a clinical focus on neuromodulation, deep transcranial magnetic stimulation (dTMS), treatment-resistant depression, mood disorders, translational neuroscience, women's mental health, and comorbid psychiatric disorders. My research focuses on investigating novel treatments and diagnostic tools for characterizing pathological responses to trauma, which focuses on post-traumatic stress disorder and depression. I am board certified by the American Board of Psychiatry & Neurology and a member of the American Society of Hispanic Psychiatry. Within the Department of Psychiatry and Behavioral Sciences, I am the deputy vice-chair for research. I am also co-founder of the Junior Research Faculty Peer Mentoring Group and the Early Career Investigator Peer Mentoring Group.

Expertise

PTSD

Administrative Assistant

(for academic support only)
Natasha Hampton-Anderson
nhampton@umn.edu

In the Media

2024: Starred in this Medical School monthly series Where Discovery Creates Hope article titled, "Caring for Becky: Fighting Back and Finding Hope"
2021: Featured in this Time Magazine article titled, "I'm Supposed To Be in a Wedding. Will I Risk Bringing COVID-19 Home to My Kids?"
2021: Talked about PTSD with the U and about feeling nervous about returning to our normal activities, especially crowded events such as the State Fair, in this Minneapolis StarTrib article titled, "Nervous about resuming activities? How to manage 'COVID transition anxiety".
2021: Interviewed by Scripps National News about the concept of vaccine passports.
2021: Quoted in a MINNPOST piece titled, "Clinic founders tout the promise of psychedelics for mental illness; observers urge caution". She was one of the ones urging caution. Dr. Albott was also featured in this piece for the Denver Channel titled, "Vaccine passports are not a new concept but they're never without debate".
2021: Continues to help everyone understand how to process emotions around getting the COVID-19 vaccination in this Fox News 9 interview and on Minnesota Public Radio, "Feeling guilty, anxious about your COVID-19 vaccine search? You're not alone" and on WTIP radio.
2021: Featured in this M News and Events item, "Talking vaccine anxiety, guilt and shaming with the U of M".
2021: Featured in a Today’s Hospitalist article titled, Making sure clinicians stay connected, about the work she helped do with the Battle Buddy program.
2021: Quoted in a Minneapolis Star Tribune story titled, "Minnesota's long haul: One year of COVID-19".

Research Summary

Dr. Albott investigates novel treatments and diagnostic tools for characterizing pathological responses to trauma, with a focus on post-traumatic stress disorder and depression. She is specifically interested in using both pharmacological and neuromodulation interventions for understanding response and relapse to effective treatments using multimodal analytic methodologies.

Clinical Summary

Neuromodulation; Trauma-related disorders; Mood disorders

Education

MA, Catholic University of Louvain

Major: Philosophy

MD, University of Minnesota Medical School

Fellowships, Residencies, and Visiting Engagements

Psychiatry, Residency

University of Minnesota Medical Center

Licensures and Certifications

Basic Cardiac Life Support

Operator of Deep TMS

American Board of Psychiatry and Neurology Diplomate

Honors and Recognition

American Medical Student Organization, Universal Health Care & Health Care Policy Leadership Institute

Minneapolis Top Doctors Rising Stars - 2024, Mpls/St.Paul Magazine

Flemish Community Fellowship, Ministry of Flemish Community, Belgium

European Union Summer School on Risk Assessment for Reproduction, Advanced Course in Human Reproduction, Epidemiology - Full Scholarship

Minneapolis Top Doctors: Rising Stars - 2023, Mpls.St. Paul Magazine

NIH Loan Repayment Award Recipient in Clinical Research (multiple)

ASCP Fellowship for Workshop on Clinical Trials in Psychopharmacology

ADAA Alies Muskin Career Development Leadership Program

Society for Biological Psychiatry Chair’s Choice Award

APA Research Colloquium Junior Investigator Award

Harold Lawn Resident Teacher of the Year Award

Professional Memberships

Minnesota Psychiatric Society (MPS)

American Medical Association (AMA)

American Psychiatric Association (APA)

Association of Women Psychiatrists

American Society of Clinical Psychopharmacology (ASCP)

Anxiety and Depression Association of America (ADAA)

American Society of Hispanic Psychiatry

Languages

Spanish

Selected Publications

Albott, C., Lee, S., Cullen, K., Thuras, P., Lissek, S., Wels, J., Friedrich, K., Krueger, A., Lim, K., 2021. Characterization of Comorbid Posttraumatic Stress Disorder and Major Depressive Disorder Using Ketamine as an Experimental Medicine Probe. Journal of Psychiatry and Brain Science, 3 (6):

doi: https://doi.org/10.20900/jpbs.20210012 PubMed ID: 34632081.

Shiroma, P. R., Thuras, P., Wels, J., Albott, C. S., Erbes, C., Tye, S., Lim, K. O., 2020. Neurocognitive performance of repeated versus single intravenous subanesthetic ketamine in treatment resistant depression. Journal of affective disorders, 227 470-477.

doi: https://doi.org/10.1016/j.jad.2020.08.058 PubMed ID: 32871537.

Thai, M., Başgöze, Z., Klimes-Dougan, B., Mueller, B. A., Fiecas, M., Lim, K. O., Albott, C. S., Cullen, K. R., 2020. Neural and Behavioral Correlates of Clinical Improvement to Ketamine in Adolescents With Treatment Resistant Depression. Frontiers in Psychiatry, 11 (820):

doi: https://doi.org/10.3389/fpsyt.2020.00820 PubMed ID: 33013493.

Roy, A., Thai, M., Klimes-Dougan, B., Westlund Schreiner, M., Mueller, B., Albott, C., Lim, K., Roback, M., Fiecas, M., Tye, S., Cullen, K., 2020. Neuroplasticity markers of clinical response to ketamine in adolescents with treatment-resistant depression: Entropy and insulin-dependent mTOR activation. Journal of Psychopharmacology, 35 (2): 168-177.

doi: https://doi.org/10.1177/0269881120928203 PubMed ID: 32643995.

Albott, C. S., Wozniak, J. R., McGlinch, B. P., Wall, M. H., Gold, B. S., Vinogradov, S., 2020. Battle Buddies: Rapid Deployment of a Psychological Resilience Intervention for Health Care Workers During the COVID-19 Pandemic. Anesthesia & Analgesia, 131 (1): 43-54.

doi: https://doi.org/10.1213/ANE.0000000000004912 PubMed ID: 32345865.

Shiroma, P. R., Thuras, P., Wels, J., Albott, C. S., Erbes, C., Tye, S., Lim, K. O., 2020. A randomized, double-blind, active placebo-controlled study of efficacy, safety, and durability of repeated vs single subanesthetic ketamine for treatment-resistant depression. Translational Psychiatry, 10 (1):

doi: https://doi.org/10.1038/s41398-020-00897-0 PubMed ID: 32591496.

Albott, C. S., Forbes, M. K., Anker, J. J., 2018. Association of Childhood Adversity With Differential Susceptibility of Transdiagnostic Psychopathology to Environmental Stress in Adulthood. JAMA network open, 1 (7):

doi: http://dx.doi.org/10.1001/jamanetworkopen.2018.5354 PubMed ID: 30646399.

Cullen, K. R., Amatya, P., Roback, M. G., Albott, C. S., Westlund Schreiner, M., Ren, Y., Eberly, L. E., Carstedt, P., Samikoglu, A., Gunlicks-Stoessel, M., Reigstad, K., Horek, N., Tye, S., Lim, K. O., Klimes-Dougan, B., 2018. Intravenous Ketamine for Adolescents with Treatment-Resistant Depression: An Open-Label Study. Journal of Child and Adolescent Psychopharmacology, 28 (7): 437-444.

doi: https://doi.org/10.1089/cap.2018.0030 PubMed ID: 30004253.

Albott, C. S., Lim, K. O., Forbes, M. K., Erbes, C., Tye, S. J., Grabowski, J. G., Thuras, P., Batres-Y-Carr, T. M., Wels, J., Shiroma, P. R., 2018. Efficacy, Safety, and Durability of Repeated Ketamine Infusions for Comorbid Posttraumatic Stress Disorder and Treatment-Resistant Depression. The Journal of Clinical Psychiatry, 79 (3):

doi: http://dx.doi.org/10.4088/JCP.17m11634 PubMed ID: 29727073.

Shiroma, P. R., Albott, C. S., Johns, B., Thuras, P., Wels, J., Lim, K. O., 2015. The Effect of Repeated Ketamine Infusion Over Facial Emotion Recognition in Treatment-Resistant Depression: A Preliminary Report. The Journal of Neuropsychiatry and Clinical Neurosciences, 27 (4): 362-364.

doi: https://doi.org/10.1176/appi.neuropsych.14100243 PubMed ID: 25658681.

Selected Presentations

Albott, C. S. R., Vinogradov, S. "Mental Health Effects of the Pandemic.", Emerging Infections in Clinical Practice and Public Health, University of Minnesota Department of Infectious Disease, Minneapolis, Minnesota, United States. November 20, 2021.

Albott, C. S. R. "Combination Treatment with Transcranial Magnetic Stimulation and Ketamine for Treatment-resistant Depression.", Clinical TMS Society Grand Rounds, February 01, 2021.

Albott, C. S. R., Wozniak, J. R. "Mental Health Effects of the Pandemic.", Minneapolis City of Lakes Rotary Club, Minneapolis, United States. January 27, 2021.

Albott, C. S. R. "Modeling Recovery from PTSD & Depression: Ketamine as an “Experimental Medicine” Probe.", VA Medical Center Leadership Meeting, Minneapolis, Minnesota, United States. December 17, 2020.

Albott, C. S. R. "Emerging Infections in Clinical Practice and Public Health", University of Minnesota Department of Infectious Disease, Minneapolis, Minnesota, United States. November 20, 2020.

Albott, C. S. R., Gold, B., McGlinch, Vinogradov, S., Wozniak, J. R. "The Minnesota Resilience Action Plan (MinnRAP): Future Directions (Part 2).", ECHO Institute First Responder, Albuquerque, New Mexico, United States. September 01, 2020.

Albott, C. S. R., Gold, B., McGlinch, Vinogradov, S., Wozniak, J. R. "The Minnesota Resilience Action Plan (MinnRAP): Introduction (Part 1).", ECHO Institute First Responder, Albuquerque, New Mexico, United States. September 01, 2020.

Warlick, C., Vinogradov, S., Wozniak, J. R., Albott, C. S. R. "How do we honor our feelings and transform our anger, grief, and fear into meaningful action…when we are exhausted from the pandemic?", Special Topic Grand Rounds, Minneapolis, Minnesota, June 02, 2020.

Albott, C. S. R., Pacala, J., Miller, J. "Dean’s Virtual Town Hall: University of Minnesota’s rapid response to COVID-19.", Minneapolis, Minnesota, June 01, 2020.

Albott, C. S. R., Roy, A., Shiroma, P., Thuras, P., Wels, J., Lim, K. "Comparison of Large-scale Network Changes Associated with Remission of Depression to Ketamine: Comparison of 6 infusions to 1 infusion.", American College of Neuropsychopharmacology 58th Annual Meeting, Orlando, Florida, December 05, 2019.

Contact

Address

Department of Psychiatry & Behavioral Sciences, F282/2A West Building, 2450 Riverside Avenue South, Minneapolis, MN 55454

C. Sophia Albott , Credentials MD, MA

Bio