Anna Prizment, PhD

Associate Professor of Medicine, Division of Hematology, Oncology and Transplantation

Anna Prizment

Contact Info

Mailing Address:
420 Delaware Street SE, MMC 480, Minneapolis, MN 55455

Administrative Assistant Name
Pam Hansen

Administrative Email
hanse032@umn.edu

Associate Professor of Medicine, Division of Hematology, Oncology and Transplantation


Postdoctoral Research Fellowship in Ruth L. Kirchstein T32 Grant (Nutrition and Cancer), University of Minnesota, Minneapolis, MN

PhD, Epidemiology, University of Minnesota School of Public Health

MPH, Epidemiology, University of Minnesota School of Public Health

MS, Chemistry, Moscow State University

BS, Chemistry, Moscow State University

Summary

As a cancer epidemiologist, I study cancer prevention and survival of cancer patients, and my research has two closely related foci. The first focus is the role of inflammation and immune response, as measured by circulating and tissue biomarkers, genetic alterations and gut microbiome, in gastrointestinal cancers. My second focus is the role of aspirin and other anti-inflammatory agents in colorectal cancer. Although most of my studies are in gastrointestinal cancers, I am also interested in studying other types of cancer (e.g. prostate, breast) including risk factors for their development and survival.

Expertise

  • Inflammatory and immune biomarkers in gastrointestinal cancers
  • Gut microbiome
  • Genetics
  • Survival of cancer patients
  • Ageing and chronic diseases

Awards & Recognition

  • Teaching Recognition, Division of Epidemiology and Community Health (2018)
  • Brainstorm Award, Masonic Cancer, University of Minnesota (2016)
  • Grant-in-Aid Award of Research, Artistry & Scholarship Program, Office of the Vice President for Research, University of Minnesota (2015)
  • CTSI KL2 Translational Science Award, University of Minnesota (2013)
  • American Cancer Society Institutional Research Award (2014)
  • J.B. Hawley Research Award, University of Minnesota (2011)
  • American Association for Cancer Research (AACR) Scholar-in-Training Award (2011)
  • American Association for Cancer Research (AACR) Scholar-in-Training Award (2009)

Professional Associations

  • Member, American Society for Hematology 2008-present
  • Society of Epidemiological Research; American Association for Cancer Research (AACR)
  • American AACR Molecular Epidemiology Working Group
  • The Pancreatic Cancer Case-Control Consortium (PanC4) 

Research

Research Summary/Interests

  • The immune response and survival of colorectal patients
  • Role of germline mutations in colorectal and pancreatic cancers
  • Clinical trials on anti-inflammatory agents and gut microbiome
  • Quality of life and cardiovascular health of cancer patients
  • Role of obesity, diabetes and other comorbidities in cancer development and survival 

Research Funding Grants

  • The Effect of Ginger on the Gut Microbiome, Minnesota Cancer Clinical Trials Network (MNCCTN) & Masonic Cancer Center, PI
  • The Role of Germline CFTR Mutations in Colorectal Cancer, Whiteside Institute for Clinical Research, AHC Faculty Development Research Grant, Co-PI
  • The 10,000 Family Study, Masonic Cancer Center, Co-I
  • The Role of the Intestinal Microbiota in Cancer Pathogenesis and Clinical Care, Co-I 

Publications

See a full list of publications on PubMed

Select Recent Publications

  • Polter E, Onyeaghala GC, Lutsey PL, Folsom AR, Joshu CE, Platz EA, Prizment AE. Prospective Association of Serum and Dietary Magnesium with Colorectal Cancer Incidence. Cancer Epidemiol Biomarkers Prev. 2019 Jun 5. pii: cebp.1300.2018. doi: 10.1158/1055-9965.EPI-18-1300. [Epub ahead of print] PMID: 31167754
  • 2. Onyeaghala G, Lane J, Pankratz N, Nelson HH, Thyagarajan B, Walcheck B, Anderson KE, Prizment AE. Association between MICA polymorphisms, s-MICA levels, and pancreatic cancer risk in a population-based case-control study. PLoS One. 2019 Jun 5;14(6):e0217868. doi: 10.1371/journal.pone.0217868. eCollection 2019.PMID: 31166958
  • 3.Um CY, Prizment A, Hong CP, Lazovich D, Bostick RM. Associations of calcium and dairy product intakes with all-cause, all-cancer, colorectal cancer and CHD mortality among older women in the Iowa Women's Health Study. Br J Nutr. 2019 May;121(10):1188-1200. doi: 10.1017/S000711451900045X. Epub 2019 Mar 5.PMID: 30834851
  • 4. Rooney MR, Lutsey PL, Bhatti P, Prizment A. Urinary 2,5-dicholorophenol and 2,4-dichlorophenol concentrations and prevalent disease among adults in the National Health and Nutrition Examination Survey (NHANES). Occup Environ Med. 2018 Oct 30. pii: oemed-2018-105278. doi: 10.1136/oemed-2018-105278 [Epub ahead of print]. PMID: 29975407
  • 5. Oyenuga M, Yang JK, Prizment AE, Bushhouse S, Demerath E, Spector LG. Cancer in the Hmong Population in Minnesota. Cancer 2018; 1;124(17):3560-3566. doi: 10.1002/cncr.31592. Epub 2018 Jul 5. doi: 10.1002/cncr.31592. [Epub ahead of print] PMID: 29975407
  • 6. Onyeaghala G, Nelson HH, Thyagarajan B, Linabery AM, Panoskaltsis-Mortari A, Gross M, Anderson KE, Prizment AE. Soluble MICA levels are higher in pancreatic cancer cases than controls. Molecular Carcinogenesis. 2017;56(9):2158-64. PMCID: PMC559063
  • 7. Prizment AE, Vierkant RA, Smyrk TC, Tillmans LS, Nelson HH, Lynch CF, Pengo T Thibodeau SN, Church TR, Cerhan JR, Anderson KE, Limburg PJ. Cytotoxic T-cells and granzyme B associated with improved colorectal cancer survival in a prospective cohort of older women. Cancer Epidemiology, Biomarkers & Prevention. 2017;26(4):622-31. PMCID: PMC5380516
  • 8. Prizment AE, Vierkant RA, Smyrk TC, Tillmans LS, Lee JJ, Sriramarao P, Nelson HH, Lynch CF, Thibodeau SN, Church TR, Cerhan JR, Anderson KE, Limburg PJ. Tumor eosinophil infiltration and improved survival of colorectal cancer patients in the Iowa Women’s Health Study. Modern Pathology. 2016;29(5):516-27. PMCID: PMC4848192
  • 9. Koene R, Prizment AE, Blaes A, Konety S. Shared risk factors in cardiovascular disease and cancer. Circulation. 2016;133(11):1104-14. PMCID: PMC4800750
  • 10. Prizment AE, Linabery AM, Lutsey PL, Selvin E, Nelson HH, Folsom AR, Church TR, Platz EA, Joshu CE. Circulating beta-2 microglobulin and risk of cancer: The Atherosclerosis Risk in Communities Study (ARIC). Cancer Epidemiology, Biomarkers & Prevention. 2016;25(4):657-64. PMCID: PMC4873421
     

Teaching

Courses

  • PUBH 6355
    Pathophysiology of Human Disease (Cancer Unit)