Jesse Seegmiller

Assistant Professor


Dr. Seegmiller is a board certified clinical chemist in the Department's Division of Clinical Chemistry. He focuses his research activities on esoteric testing where he primarily employs mass spectrometry to analyze and develop methods for biological samples in the Advanced Research and Diagnostics Laboratory (ARDL).Before his fellowship and faculty appointment Dr. Seegmiller worked in industry for a mass spectrometry company as a Product Applications Specialist in Clinical Applications. Prior to that he worked in the Department of Laboratory Medicine at Mayo Clinic.

Research Summary

Dr. Seegmiller is an analytical chemist in the Department's Division of Clinical Chemistry.  He focuses his research activities mainly on mass spec analysis of biological samples in the Advanced Research and Diagnostics Laboratory (ARDL).


Seegmiller JC, Kokaisel EL, Story SJ, Zaun CP, Peters JM, Thomas SN, and Karger AB. Method comparison of SARS-CoV-2 serology assays involving three commercially available platforms and a novel in-house developed enzyme-linked immunosorbent assay Clin Biochem. 2020;S0009-9120(20)30812-2. doi:10.1016/j.clinbiochem.2020.08.004.

Seegmiller JC, Eckfeldt JH, Lieske JC. Challenges in Measuring Glomerular Filtration Rate: A Clinical Laboratory Perspective. Adv Chronic Kidney Dis. 2018 Jan;25(1):84-92. doi: 10.1053/j.ackd.2017.10.006

Seegmiller JC, Miller WG, Bachmann LM. Moving Toward Standardization of Urine Albumin Measurements. EJIFCC. 2017 Dec 19;28(4):258-267. eCollection 2017 Dec.

Schwartz GJ, Wang H, Erway B, Nordin G, Seegmiller J, Lieske JX, Bäck S-E, Miller WG, Eckfeldt JH. Multicenter Laboratory Comparison of Iohexol Measurement. The Journal of Applied Laboratory Medicine Mar 2018, 2 (5) 711-724; DOI: 10.1373/jalm.2017.024240

Love SA, Seegmiller JC, Kloss J, Apple FS. Urine Creatinine Concentrations in Drug Monitoring Participants and Hospitalized Patients. J Anal Toxicol. 2016 Sep 1-4.

Larson TS, Seegmiller J, In Reply to 'Iohexol Versus Iothalamate for GFR Measurement'. Am J Kidney Dis. 2016 Jun;67(6):991-2.


PhD, Analytical Chemistry, University of Wyoming, 2004

Fellowships, Residencies, and Visiting Engagements




D185 Mayo
420 Delaware St. SE
Minneapolis, MN 55455