Jop van Berlo
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Credentials
MD, PhD
Bio
Administrator Info
Name: Esther Almeida
Email: ealmeida@umn.edu
Mail: Lillehei Heart Institute
2231 6th Street SE
1st-floor Mailroom CCRB
Minneapolis, Minnesota 55455
Summary
After obtaining his M.D. and Ph.D. degrees from the University of Maastricht, the Netherlands, Dr. Jop van Berlo performed postdoctoral research with Dr.Jeffery Molkentin at the Howard Hughes Medical Institute, Cincinnati Children's Hospital Medical Center. Upon joining the University of Minnesota he has built a research program focused on the cellular and molecular mechanisms of cardiac remodeling and regeneration. An active area of research is on the role of the immune system in orchestrating cardiac remodeling. Separately, the laboratory is interested in discovering regulators of cardiomyocyte proliferation.
Research Summary
My laboratory studies the cellular and molecular mechanisms of cardiac remodeling and regeneration. The goal of this research is to develop innovative strategies to enhance the limited ability of the heart to regenerate and stimulate reverse remodeling. To identify these strategies, we study the underlying mechanisms of endogenous remodeling and regeneration in mice. We are currently interested in discovering novel regulators of cardiomyocyte proliferation. We have candidate regulators that we are verifying in cell culture and in genetic mouse models. Furthermore, we are interested in the role of the immune system in orchestrating remodeling and regeneration.