Laura Stone, PhD

Pruinelli L, Mathiason MA, Ma S, Stalter N, Stone L, Fillingim RB, Setty S, Banik RK. Age Differences in Patients With Postoperative Pain and Their Relationships to Comorbid Conditions: Multivariate Logistic Regression Analysis. AANA J. 2025 Oct 1;93(5):331-337. doi: 10.70278/AANAJ/.0000001024. PMID: 41056143.

Schorn R, Riedl M, Stone LS, Lee AM, Vulchanova L. Chronic alcohol drinking delays recovery from capsaicin- and nerve injury-induced hypersensitivity in mice. Alcohol. 2025 Dec;129:123-133. doi: 10.1016/j.alcohol.2025.10.001. Epub 2025 Oct 4. PMID: 41052586.

Osagie RO, Tufa I, Angarita-Fonseca A, Pagé MG, Lacasse A, Stone LS, Rainville P, Roy M, Tétreault P, Fortin M, Léonard G, Massé-Alarie H, Roy JS, Grant AV, Meloto CB; Quebec Back Pain Consortium. Impact of different acute low back pain definitions on the predictors and on the risk of transition to chronic low back pain: a prospective longitudinal cohort study. Pain. 2025 Nov 1;166(11):e577-e589. doi: 10.1097/j.pain.0000000000003669. Epub 2025 Jun 11. PMID: 40663110; PMCID: PMC12519535.

Roberts JB, Rockel JS, Mulders R, Capellini TD, Appleton CT, Phanstiel DH, Lories R, Geurts J, Ali SA, Bhutani N, Stone L, Cruz-Almeida Y, Jurisica I, Boer CG, Ramos YFM, Rice SJ, Kapoor M. From mechanism to medicine: The progress and potential of epigenetics in osteoarthritis. Osteoarthr Cartil Open. 2025 Apr 29;7(3):100621. doi: 10.1016/j.ocarto.2025.100621. PMID: 40487807; PMCID: PMC12142501.

Mannarino M, Cherif H, Ghazizadeh S, Martinez OW, Sheng K, Cousineau E, Lee S, Millecamps M, Gao C, Gilbert A, Peirs C, Naeini RS, Ouellet JA, S Stone L, Haglund L. Senolytic treatment for low back pain. Sci Adv. 2025 Mar 14;11(11):eadr1719. doi: 10.1126/sciadv.adr1719. Epub 2025 Mar 14. PMID: 40085710; PMCID: PMC11908501.

Yeater TD, Kawarai Y, Lee S, Belani KG, Beebe DS, Sheyn D, Pinto MR, Stone LS. Investigating the epigenetic landscape of symptomatic disk degeneration: a case study. Pain Rep. 2025 Feb 21;10(2):e1237. doi: 10.1097/PR9.0000000000001237. PMID: 39995491; PMCID: PMC11850048.

Kaneda G, Huang D, Pham N, Gonzalez AR, Tawackoli W, Lee S, Suzuki M, Nelson TJ, Glaeser JD, Millecamps M, Stone LS, Sheyn D, Metzger MF. Exercise improves load bearing bone structural properties in female secreted protein acidic and rich in cysteine (SPARC) null mice but not in males. J Orthop Res. 2024 Dec;42(12):2725-2734. doi: 10.1002/jor.25950. Epub 2024 Aug 6. PMID: 39105654; PMCID: PMC12014150.

Jenkins LC, Chang WJ, Humburg P, Wasinger VC, Stone LS, Dorsey SG, Renn C, Starkweather A, Schabrun SM. Sex Differences in the Serum Proteomic Profile During Acute Low Back Pain-A Preliminary Study of the Relationship to Future Low Back Pain. J Pain. 2024 May;25(5):104426. doi: 10.1016/j.jpain.2023.11.009. Epub 2023 Nov 19. PMID: 37989405.

Barbe MF, Chen FL, Loomis RH, Harris MY, Kim BM, Xie K, Hilliard BA, McGonagle ER, Bailey TD, Gares RP, Van Der Bas M, Kalicharan BA, Holt-Bright L, Stone LS, Hodges PW and Klyne DM (2024) Characterization of pain-related behaviors in a rat model of acute-to-chronic low back pain: single vs. multi-level disc injury. Front. Pain Res. 5:1394017. doi: 10.3389/fpain.2024.1394017

Koroth Jinsha , Chitwood Casey , Kumar Ramya , Lin Wei-Han , Reves Benjamin T. , Boyce Todd , Reineke Theresa M. , Ellingson Arin M. , Johnson Casey P. , Stone Laura S. , Chaffin Kimberly C. , Simha Narendra K. , Ogle Brenda M. , Bradley Elizabeth W. Identification of a novel, MSC-induced macrophage subtype via single-cell sequencing: implications for intervertebral disc degeneration therapy. Frontiers in Cell and Developmental Biology. DOI 10.3389/fcell.2023.1286011

Bussières A, Hancock MJ, Elklit A, Ferreira ML, Ferreira PH, Stone LS, Wideman TH, Boruff JT, Al Zoubi F, Chaudhry F, Tolentino R, Hartvigsen J. Adverse childhood experience is associated with an increased risk of reporting chronic pain in adulthood: a stystematic review and meta-analysis. Eur J Psychotraumatol. 2023;14(2):2284025. doi: 10.1080/20008066.2023.2284025. Epub 2023 Dec 18. PMID: 38111090; PMCID: PMC10993817.

Whittal, M., Poynter, S., Samms, K., Briar, K.J., Sinopoli, S., Millecamps, M., Stone, L.S., DeWitte-Orr, S., Gregory, D., 2022. TAK-242 treatment and its effect on mechanical properties and gene expression associated with IVD degeneration in SPARC-null mice. European Spine Journal, 31 (10)
doi: https://doi.org/10.1007/s00586-022-07310-y

Bolt, J., Patel, F., Stone, L.S., Pandian, D., Manuel, M., Gaines, N., 2022. Impact of COVID-19 on pediatric mental and behavioral health visits to the emergency department. Pediatric Emergency Care, 38 (8)
doi: https://doi.org/10.1097/PEC.0000000000002794

Angarita-Fonseca, A., Pagé, G., Meloto, C., Gentile, E.L., Léonard, G., Massé-Alarie, H., Tufa, L., Roy, J.S., Stone, L.S., Choinière, M., Fortin, M., Roy, M., Sean, M., Tétreault, P., Rainville, P., Deslauriers, S., Lacasse, A., 2022. The Canadian version of the NIH minimum dataset for chronic low back pain research: Reference values from the Quebec Low Back Pain Study. PAIN, 
doi: https://doi.org/10.1097/j.pain.0000000000002703

Millecamps, M., Sotocinal, S., Austin, J.S., Stone, L.S., Mogil, J.S., 2022. Sex-specific effects of neuropathic pain on long-term pain behavior and mortality in mice. PAIN, 
doi: https://doi.org/10.1097/j.pain.0000000000002742

Lee, S., Kawarai, Y., Ouellet, J., Haglund, L., Szyf, M., Stone, L.S., 2022. DNA methylation in degenerating human intervertebral discs. Journal of Pain, 23 (5)
doi: https://doi.org/10.1016/j.jpain.2022.03.148

Millecamps, M., Gregoire, S., Stone, L.S., 2022. Inter- and trans-generational inheritance of paternal chronic pain to male and female offspring in mice. Journal of Pain, 23 (5)
doi: https://doi.org/10.1016/j.jpain.2022.03.102

Buck, E., Lee, S., Gao, Q., Tran, S., Tamimi, F., Stone, L.S., Cerruti, M., 2022. The role of surface chemistry in the osseointegration of peek implants. ACS Biomaterials Science and Engineering, 8 (4)
doi: https://doi.org/10.1021/acsbiomaterials.1c01434

Massé-Alarie, H., Angarita-Fonseca, A., Lacasse, A., Pagé, G., Tétreault, P., Fortin, M., Léonard, G., Stone, L.S., Roy, J.S., 2022. Low back pain definitions: Effect on patient inclusion and clinical profiles. Pain Reports, 7 (2)
doi: https://doi.org/10.1097/PR9.0000000000000997

Grégoire, S., Cheishvili, D., Salmon-Divon, M., Dymov, S., Topham, L., Calderon, V., Shir, Y., Szyf, M., Stone, L.S., 2021. Epigenetic signature of chronic low back pain in human T cells. Pain Reports, 6 (4)
doi: https://doi.org/10.1097/PR9.0000000000000960

Kawarai, Y., Jang, S. H., Lee, S., Millecamps, M., Kang, H., Gregoire, S., Suzuki-Narita, M., Ohtori, S., Stone, L.S., 2021. Exercise attenuates low back pain and alters epigenetic regulation in intervertebral discs in a mouse model. The Spine Journal, 21 (11)
doi: https://doi.org/10.1016/j.spinee.2021.06.002

Lee, S., Jang, S.H., Suzuki-Narita, M., Gregoire, S., Millecamps, M., Stone, L.S., 2021. Voluntary running attenuates behavioural signs of low back pain: dimorphic regulation of intervertebral disc inflammation in male and female SPARC-null mice. Osteoarthritis and Cartilage, 
doi: https://doi.org/10.1016/j.joca.2021.06.014

Millecamps, M., Lee, S., Foster, D.Z., Stone, L.S., 2021. Disc degeneration spreads: Long-term behavioural, histologic and radiologic consequences of a single-level disc injury in active and sedentary mice. European Spine Journal, 30 (8)
doi: https://doi.org/10.1007/s00586-021-06893-2

Kawarai, Y., Jang, S.H., Lee, S., Millecamps, M., Kang, H., Gregoire, S., Suzuki-Narita, M., Ohtori, S., Stone, L.S., 2021. Exercise attenuates low back pain and alters epigenetic regulation in intervertebral discs in a mouse model. The Spine Journal, 
doi: https://doi.org/10.1016/j.spinee.2021.06.002

James, G., Millecamps, M., Stone, L.S., Hodges, P.W., 2021. Multifidus muscle fibre type distribution is changed in mouse models of chronic intervertebral disc degeneration, but is not attenuated by whole body physical activity. Spine, 
doi: https://doi.org/10.1097/BRS.0000000000004105

Jang, S., Millecamps, M., Danco, A, Kang, H.M., Grégoire, S., Suzuki-Narita, M., Stone, L.S., 2021. Effect of voluntary running activity on mRNA expression of extracellular matrix genes in a mouse model of intervertebral disc degeneration. JOR Spine, 4 (3)
doi: https://doi.org/10.1002/jsp2.1148

Kerr, G.J., To, B., White, I., Millecamps, M., Beier, F., Grol, M.W., Stone, L.S., Séguin, C.A., 2021. Diet-induced obesity leads to behavioral indicators of pain preceding structural joint damage in wild-type mice. Arthritis Research and Therapy, 23 (1): 93. 
doi: https://doi.org/10.1186/s13075-021-02463-5

Buck, E., Lee, S., Stone, L.S., Cerruti, M., 2021. Protein adsorption on surfaces functionalized with COOH groups promotes anti-inflammatory macrophage responses. ACS Applied Materials and Interfaces, 13 (6)
doi: https://doi.org/10.1021/acsami.0c16509

Whittal, M.C., Molladavoodi, S., Zwambag, D.P., Millecamps, M., Stone, L.S., Gregory, D.E., 2021. Mechanical consequence of induced intervertebral disc degeneration in the SPARC-null mouse. Journal of Biomechanical Engineering, 143 (2)
doi: https://doi.org/10.1115/1.4047995