Laura Stone
,

Credentials

PhD

Professor

Biography

Bio

Dr. Laura Stone is a professor in the Department of Anesthesiology at the University of Minnesota. She received a Bachelor of Science in biochemistry from the University of California-San Diego and PhD in neuroscience from the University of Minnesota.

Research Summary

Dr. Stone's research interests include the mechanisms of pain, epigenetic regulation of chronic pain, and pharmacological and non-pharmacological methods of treatment.

Education

PhD, University of Minnesota

Professional Memberships

Society for Neuroscience

International Association for the Study of Pain

US Association for the Study of Pain

Canadian Pain Socitey

Orthopedics Research Society

Selected Publications

Whittal, M., Poynter, S., Samms, K., Briar, K.J., Sinopoli, S., Millecamps, M., Stone, L.S., DeWitte-Orr, S., Gregory, D., 2022. TAK-242 treatment and its effect on mechanical properties and gene expression associated with IVD degeneration in SPARC-null mice. European Spine Journal, 31 (10):

doi: https://doi.org/10.1007/s00586-022-07310-y

Bolt, J., Patel, F., Stone, L.S., Pandian, D., Manuel, M., Gaines, N., 2022. Impact of COVID-19 on pediatric mental and behavioral health visits to the emergency department. Pediatric Emergency Care, 38 (8):

doi: https://doi.org/10.1097/PEC.0000000000002794

Angarita-Fonseca, A., Pagé, G., Meloto, C., Gentile, E.L., Léonard, G., Massé-Alarie, H., Tufa, L., Roy, J.S., Stone, L.S., Choinière, M., Fortin, M., Roy, M., Sean, M., Tétreault, P., Rainville, P., Deslauriers, S., Lacasse, A., 2022. The Canadian version of the NIH minimum dataset for chronic low back pain research: Reference values from the Quebec Low Back Pain Study. PAIN,

doi: https://doi.org/10.1097/j.pain.0000000000002703

Millecamps, M., Sotocinal, S., Austin, J.S., Stone, L.S., Mogil, J.S., 2022. Sex-specific effects of neuropathic pain on long-term pain behavior and mortality in mice. PAIN,

doi: https://doi.org/10.1097/j.pain.0000000000002742

Lee, S., Kawarai, Y., Ouellet, J., Haglund, L., Szyf, M., Stone, L.S., 2022. DNA methylation in degenerating human intervertebral discs. Journal of Pain, 23 (5):

doi: https://doi.org/10.1016/j.jpain.2022.03.148

Millecamps, M., Gregoire, S., Stone, L.S., 2022. Inter- and trans-generational inheritance of paternal chronic pain to male and female offspring in mice. Journal of Pain, 23 (5):

doi: https://doi.org/10.1016/j.jpain.2022.03.102

Buck, E., Lee, S., Gao, Q., Tran, S., Tamimi, F., Stone, L.S., Cerruti, M., 2022. The role of surface chemistry in the osseointegration of peek implants. ACS Biomaterials Science and Engineering, 8 (4):

doi: https://doi.org/10.1021/acsbiomaterials.1c01434

Massé-Alarie, H., Angarita-Fonseca, A., Lacasse, A., Pagé, G., Tétreault, P., Fortin, M., Léonard, G., Stone, L.S., Roy, J.S., 2022. Low back pain definitions: Effect on patient inclusion and clinical profiles. Pain Reports, 7 (2):

doi: https://doi.org/10.1097/PR9.0000000000000997

Grégoire, S., Cheishvili, D., Salmon-Divon, M., Dymov, S., Topham, L., Calderon, V., Shir, Y., Szyf, M., Stone, L.S., 2021. Epigenetic signature of chronic low back pain in human T cells. Pain Reports, 6 (4):

doi: https://doi.org/10.1097/PR9.0000000000000960

Kawarai, Y., Jang, S. H., Lee, S., Millecamps, M., Kang, H., Gregoire, S., Suzuki-Narita, M., Ohtori, S., Stone, L.S., 2021. Exercise attenuates low back pain and alters epigenetic regulation in intervertebral discs in a mouse model. The Spine Journal, 21 (11):

doi: https://doi.org/10.1016/j.spinee.2021.06.002

Whittal, M.C., Molladavoodi, S., Zwambag, D.P., Millecamps, M., Stone, L.S., Gregory, D.E., 2021. Mechanical consequence of induced intervertebral disc degeneration in the SPARC-null mouse. Journal of Biomechanical Engineering, 143 (2):

doi: https://doi.org/10.1115/1.4047995

Kerr, G.J., To, B., White, I., Millecamps, M., Beier, F., Grol, M.W., Stone, L.S., Séguin, C.A., 2021. Diet-induced obesity leads to behavioral indicators of pain preceding structural joint damage in wild-type mice. Arthritis Research and Therapy, 23 (1): 93.

doi: https://doi.org/10.1186/s13075-021-02463-5

Buck, E., Lee, S., Stone, L.S., Cerruti, M., 2021. Protein adsorption on surfaces functionalized with COOH groups promotes anti-inflammatory macrophage responses. ACS Applied Materials and Interfaces, 13 (6):

doi: https://doi.org/10.1021/acsami.0c16509

Jang, S., Millecamps, M., Danco, A, Kang, H.M., Grégoire, S., Suzuki-Narita, M., Stone, L.S., 2021. Effect of voluntary running activity on mRNA expression of extracellular matrix genes in a mouse model of intervertebral disc degeneration. JOR Spine, 4 (3):

doi: https://doi.org/10.1002/jsp2.1148

James, G., Millecamps, M., Stone, L.S., Hodges, P.W., 2021. Multifidus muscle fibre type distribution is changed in mouse models of chronic intervertebral disc degeneration, but is not attenuated by whole body physical activity. Spine,

doi: https://doi.org/10.1097/BRS.0000000000004105

Kawarai, Y., Jang, S.H., Lee, S., Millecamps, M., Kang, H., Gregoire, S., Suzuki-Narita, M., Ohtori, S., Stone, L.S., 2021. Exercise attenuates low back pain and alters epigenetic regulation in intervertebral discs in a mouse model. The Spine Journal,

doi: https://doi.org/10.1016/j.spinee.2021.06.002

Millecamps, M., Lee, S., Foster, D.Z., Stone, L.S., 2021. Disc degeneration spreads: Long-term behavioural, histologic and radiologic consequences of a single-level disc injury in active and sedentary mice. European Spine Journal, 30 (8):

doi: https://doi.org/10.1007/s00586-021-06893-2

Lee, S., Jang, S.H., Suzuki-Narita, M., Gregoire, S., Millecamps, M., Stone, L.S., 2021. Voluntary running attenuates behavioural signs of low back pain: dimorphic regulation of intervertebral disc inflammation in male and female SPARC-null mice. Osteoarthritis and Cartilage,

doi: https://doi.org/10.1016/j.joca.2021.06.014

Contact

Address

4-145 Jackson Hall,
321 Church Street SE,
Minneapolis, MN 55455