Laura Stone



Dr. Laura Stone is a professor in the Department of Anesthesiology at the University of Minnesota. She received a Bachelor of Science in biochemistry from the University of California-San Diego and PhD in neuroscience from the University of Minnesota.

Research Summary

Dr. Stone's research interests include the mechanisms of pain, epigenetic regulation of chronic pain, and pharmacological and non-pharmacological methods of treatment.


PhD, University of Minnesota

Professional Memberships

Society for Neuroscience
International Association for the Study of Pain
US Association for the Study of Pain
Canadian Pain Socitey
Orthopedics Research Society
Selected Publications

Selected Publications

Whittal, M., Poynter, S., Samms, K., Briar, K.J., Sinopoli, S., Millecamps, M., Stone, L.S., DeWitte-Orr, S., Gregory, D., 2022. TAK-242 treatment and its effect on mechanical properties and gene expression associated with IVD degeneration in SPARC-null mice. European Spine Journal, 31 (10):
Bolt, J., Patel, F., Stone, L.S., Pandian, D., Manuel, M., Gaines, N., 2022. Impact of COVID-19 on pediatric mental and behavioral health visits to the emergency department. Pediatric Emergency Care, 38 (8):
Angarita-Fonseca, A., Pagé, G., Meloto, C., Gentile, E.L., Léonard, G., Massé-Alarie, H., Tufa, L., Roy, J.S., Stone, L.S., Choinière, M., Fortin, M., Roy, M., Sean, M., Tétreault, P., Rainville, P., Deslauriers, S., Lacasse, A., 2022. The Canadian version of the NIH minimum dataset for chronic low back pain research: Reference values from the Quebec Low Back Pain Study. PAIN,
Millecamps, M., Sotocinal, S., Austin, J.S., Stone, L.S., Mogil, J.S., 2022. Sex-specific effects of neuropathic pain on long-term pain behavior and mortality in mice. PAIN,
Lee, S., Kawarai, Y., Ouellet, J., Haglund, L., Szyf, M., Stone, L.S., 2022. DNA methylation in degenerating human intervertebral discs. Journal of Pain, 23 (5):
Millecamps, M., Gregoire, S., Stone, L.S., 2022. Inter- and trans-generational inheritance of paternal chronic pain to male and female offspring in mice. Journal of Pain, 23 (5):
Buck, E., Lee, S., Gao, Q., Tran, S., Tamimi, F., Stone, L.S., Cerruti, M., 2022. The role of surface chemistry in the osseointegration of peek implants. ACS Biomaterials Science and Engineering, 8 (4):
Massé-Alarie, H., Angarita-Fonseca, A., Lacasse, A., Pagé, G., Tétreault, P., Fortin, M., Léonard, G., Stone, L.S., Roy, J.S., 2022. Low back pain definitions: Effect on patient inclusion and clinical profiles. Pain Reports, 7 (2):
Grégoire, S., Cheishvili, D., Salmon-Divon, M., Dymov, S., Topham, L., Calderon, V., Shir, Y., Szyf, M., Stone, L.S., 2021. Epigenetic signature of chronic low back pain in human T cells. Pain Reports, 6 (4):
Kawarai, Y., Jang, S. H., Lee, S., Millecamps, M., Kang, H., Gregoire, S., Suzuki-Narita, M., Ohtori, S., Stone, L.S., 2021. Exercise attenuates low back pain and alters epigenetic regulation in intervertebral discs in a mouse model. The Spine Journal, 21 (11):
Whittal, M.C., Molladavoodi, S., Zwambag, D.P., Millecamps, M., Stone, L.S., Gregory, D.E., 2021. Mechanical consequence of induced intervertebral disc degeneration in the SPARC-null mouse. Journal of Biomechanical Engineering, 143 (2):
Kerr, G.J., To, B., White, I., Millecamps, M., Beier, F., Grol, M.W., Stone, L.S., Séguin, C.A., 2021. Diet-induced obesity leads to behavioral indicators of pain preceding structural joint damage in wild-type mice. Arthritis Research and Therapy, 23 (1): 93.
Buck, E., Lee, S., Stone, L.S., Cerruti, M., 2021. Protein adsorption on surfaces functionalized with COOH groups promotes anti-inflammatory macrophage responses. ACS Applied Materials and Interfaces, 13 (6):
Jang, S., Millecamps, M., Danco, A, Kang, H.M., Grégoire, S., Suzuki-Narita, M., Stone, L.S., 2021. Effect of voluntary running activity on mRNA expression of extracellular matrix genes in a mouse model of intervertebral disc degeneration. JOR Spine, 4 (3):
James, G., Millecamps, M., Stone, L.S., Hodges, P.W., 2021. Multifidus muscle fibre type distribution is changed in mouse models of chronic intervertebral disc degeneration, but is not attenuated by whole body physical activity. Spine,
Kawarai, Y., Jang, S.H., Lee, S., Millecamps, M., Kang, H., Gregoire, S., Suzuki-Narita, M., Ohtori, S., Stone, L.S., 2021. Exercise attenuates low back pain and alters epigenetic regulation in intervertebral discs in a mouse model. The Spine Journal,
Millecamps, M., Lee, S., Foster, D.Z., Stone, L.S., 2021. Disc degeneration spreads: Long-term behavioural, histologic and radiologic consequences of a single-level disc injury in active and sedentary mice. European Spine Journal, 30 (8):
Lee, S., Jang, S.H., Suzuki-Narita, M., Gregoire, S., Millecamps, M., Stone, L.S., 2021. Voluntary running attenuates behavioural signs of low back pain: dimorphic regulation of intervertebral disc inflammation in male and female SPARC-null mice. Osteoarthritis and Cartilage,



4-145 Jackson Hall,
321 Church Street SE,
Minneapolis, MN 55455

Administrative Contact

Angela Chen
Executive Office & Admin. Specialist