Mai Nguyen

Assistant Professor


Mai Nguyen, MD, is a board certified orthopedic surgeon, fellowship trained in orthopedic trauma, and assistant professor at the University of Minnesota. 


  • Orthopedic trauma
  • Polytrauma

Awards & Recognition

  • Mpls.St.Paul Magazine "Top Doctor—Rising Star": 2022
  • Research mentor for the Ernst Dehne Research Award Resident – William Beaumont Army Medical Center and Texas Tech University Health Sciences Center: 2019
  • Research mentor for the Physician in Training Award-Mid-America Orthopaedic Association: 2018
  • AO Davos Fellows Initiative Recipient: 2016 
  • AO Trauma North American’s Fellows Research Grant: 2015  
  • OTA Kathy Cramer Young Clinician Memorial Scholarship Award: 2015
  • AAOS/OREF/ORS Clinician Scholar Career Development Program: 2015 
  • AO Trauma North America Resident Research Grant: 2012
  • Andrew E. Russo M.D. Memorial Award for Medical Education: 2006 
  • Phi Beta Kappa Honor Society: 2005 


  • Potter E, Fernandez I, Fillinger M, Potter D, Nguyen MP, Reich MS. Abstracts accepted for presentation at orthopaedic trauma or arthroplasty conferences: Which conference is the best indicator for future publication? JAAOS Glob Res Rev. 2019; 3 e020.
  • Nguyen MP, Reich MS. Is Varus the New Alignment Goal? J Bone Joint Surg Am. 2019; 101: 3. PMID: 30730491.
  • Reich MS, Fernandez I, Mishra A, Kafchinski L, Adler A, Nguyen MP. Diabetic control predicts surgical site infection risk in orthopaedic trauma patients. Journal of Orthopaedic Trauma. 2019. May 20. Epub ahead of print. PMID: 31188259.
  • Nguyen MP, Prayson NF, Vallier HA. Low-velocity gunshot injuries to the femur: What is the utility of stabilizing incomplete fractures? Journal of the American Academy of Orthopaedic Surgeons. 2018; Dec 5. PMID: 30531237.
  • Su CA, Nguyen MP, O’Donnell JA, Vallier HA. Outcomes of tibia shaft fractures caused by low energy gunshot wounds. Injury. 2018; May 16. PMID: 29778274.
  • Nguyen MP, Como JJ, Golob JF, Reich MS, Vallier HA. Variation in treatment of low enery gunshot injuries – A survey of OTA members. Injury. 2018; Jan 31. PMID: 29396308.
  • Nguyen MP, Reich MS, O’Donnell JA, Savakus JC, Prayson NF, Golob JF, McDonald AA, Como JJ, Vallier HA. Infection and complications after low-velocity intra-articular gunshot injuries. Journal of Orthopaedic Trauma. 2017; 6: 330. PMID: 28230571.
  • Nguyen MP, Savakus JC, O’Donnell JA, Prayson NF, Reich MS, Golob JF, McDonald AA, Como JJ, Vallier HA. Infection rates and treatment of low-velocity extremity gunshot injuries. Journal of Orthopaedic Trauma. 2017; 6: 326. PMID: 28240620.
  • Reich MS, Duong M, Breslin MA, Nguyen MP, Vallier HA. Perioperative considerations in patients with periprosthetic distal femur fractures. Iowa Orthop J. 2017; 37. PMID: 28852333.
  • Nguyen MP, Pedersen DR, Yubo G, Saltzman CL, Amendola A.Intermediate-term follow-up of patients with ankle distraction as a treatment for end stage osteoarthritis. J Bone Joint Surg Am. 2015; 97: 590. PMID: 25834084.
  • Nguyen MP, Lawler EA, Morcuende JA. A case report of bilateral mirror clubfeet and bilateral hand polydactyly. Iowa Orthop J. 2014; 34: 171. PMID: 25328478.
  • Nguyen MP, Buckwalter JA, Miller BJ. Patterns of improvement following oncologic reconstruction compared to total knee arthroplasty and revision knee arthroplasty. Iowa Orthop J. 2011; 31: 160. PMID: 22096436.
  • Johnson RW, Nguyen MP, Padalecki SS, Grubbs BG, Merkel AR, Oyajobi BO, Matrisian LM, Mundy GR, Sterling JA. TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical hedgehog signaling. Cancer Res. 2011; 71: 822. PMID: 21189326.
  • Johnson RW, Merkel AR, Danilin S, Nguyen MP, Mundy GR, Sterling JA. 6-Thioguanine inhibition of parathyroid hormone-related protein expression is mediated by Gli2. Anticancer Res. 2011; 31: 2705. PMID: 21868511.
  • Anzalone PA, Baru AR, Danielson EM, Hayes PD, Nguyen MP, Panico AF, Smith RC, Mohan RS.Bismuth Compounds in Organic Synthesis. A One Pot Synthesis of Homoallyl Ethers and Homoallyl Acetates from Aldehydes Catalyzed by Bismuth Triflate. J Org Chem. 2005; 70: 2091. PMID: 15760192.
  • Anderson ED, Ernat JJ, Nguyen MP, Palma AC, Mohan R S. Environment Friendly Organic Synthesis Using Bismuth Compounds. An Efficient Method for Carbonyl-ene Reactions Catalyzed by Bismuth Triflate. Tetrahedron Lett. 2005; 46: 7747.
  • Nguyen MP, Arnold JN, Peterson KE, Mohan RS. Environment Friendly Organic Synthesis Using Bismuth Compounds: Bismuth Triflate Catalyzed Synthesis of Substituted 3,4-Dihydro-2H-1-benzopyrans. Tetrahedron Lett. 2004; 45: 9369.

Professional Associations

  • American Academy of Orthopaedic Surgeons
  • Orthopaedic Trauma Association
  • AO Trauma North America
  • Mid-America Orthopaedic Association

Research Summary

Research Interests

In addition to her clinical interests, Dr. Nguyen is active in many aspects of medical education and scientific research. Her primary research interest is improving care quality for trauma patients. She has delivered several lectures on a variety of trauma topics in national conferences and authored multiple orthopedic research abstracts, manuscripts, and textbook chapters. Dr. Nguyen is particularly passionate about resident education having mentored medical students and residents throughout her career. 

Clinical Summary

It is my mission to provide my patients the same excellent orthopedic care that I would offer to a member of my family. No one plans to be injured in an accident. As an orthopedic traumatologist, I take the responsibility of providing compassionate, state-of-the-art care to my patients very seriously.

Board Certifications

Orthopedic Surgery

Clinical Interests

Having done all her medical training at busy level I trauma centers, Dr. Nguyen specializes in the operative treatment of general extremity fractures, peri-articular fractures, complex fractures of the pelvis and acetabulum, peri-prosthetic fractures (fractures occurring around a joint replacement), and the treatment of multiply injured patients.



Administrative Contact

Erika Whitaker
Fax: 612-273-7959

Mailing Address
Regions Hospital
640 Jackson Street
St. Paul, MN 55101