Meghan Driscoll is an Assistant Professor in the Department of Pharmacology. She is a graduate faculty member of the Molecular Pharmacology and Therapeutics (MPaT) Graduate Program, as well as the Bioinformatics and Computational Biology Graduate Program. Dr. Driscoll attended Harvey Mudd College, where she received a B.S. in Physics. She then earned a Ph.D. in Physics from the University of Maryland, working under the mentorship of Dr. Wolfgang Losert. Moving to the University of Texas Southwestern Medical Center, she joined the lab of Dr. Gaudenz Danuser as a Postdoctoral Fellow and later Instructor. Dr. Driscoll joined the Department of Pharmacology in 2022.
Cells have convoluted and dynamic morphologies. Their morphology is a critical element of the vast signaling network regulating cellular functioning. Focusing on cancer and immune cells, which are often highly dynamic, the Driscoll lab investigates how the interplay between cell morphology, dynamics, and signaling governs cell function. To visualize quick subcellular dynamics, we use state-of-the-art microscopy, especially high-resolution light-sheet microscopy. The detailed 3D movies produced by these microscopes necessitate dedicated computational pipelines, and so we develop algorithms rooted in computer graphics, computer vision and machine learning to facilitate biological discovery.
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