Siddhartha Sen

Assistant Professor


Dr. Sen is a molecular pathologist with years of experience in translating research into novel therapies that can be quickly advanced from the bench to the clinic. The primary focus of his research has been in T-cell based immunotherapy to target malignant melanoma and in the development of novel therapies targeting leukemic stem cells (LSCs) in acute myelogenous leukemia (AML). His specialties include

  • Cancer immunology and immunotherapy
  • Oncology/cancer stem cell biology and signaling pathways
  • In vivo pharmacology studies: Mouse models of leukemia and melanoma
  • High throughput screening (HTS)
  • Multi-parameter flow cytometry
  • Confocal microscopy

Research Summary


Shuang Ma; Siddhartha Sen; Rachel Jug; Xuefeng Zhang; Wan-Lin Zhang; Shuai Shen; Cheng-Qian Yu; Hong-Tao Xu; Lian-He Yang; Endi Wang. Adrenal relapse of primary central nervous system diffuse large B-cell lymphoma: Report of the first case and literature review. Medicine (Baltimore). 2018 Sep; 97(38): e12482.

Amanda Contreras; Megan V Beems; Andrew J Tatar; Siddhartha Sen; Prakrithi Srinand; Marulasiddappa Suresh; Tahra K Luther; Clifford S Cho. Co-transfer of tumor-specific effector and memory CD8+ T cells enhances the efficacy of adoptive melanoma immunotherapy in a mouse model. Journal for Immunotherapy of Cancer. 2018 May 29;6(1):4


PhD, Biochemistry and Molecular Biology, LSU Health Sciences Center, 2006
MD, University of Pune, India, 2001

Fellowships, Residencies, and Visiting Engagements

Clinical Fellow, Molecular Genetic Pathology, Baylor College of Medicine, 2021,
Residency in Anatomic and Clinical Pathology, Duke University, 2020,

Licensures and Certifications

Molecular Pathology,



Mayo Memorial Building
420 Delaware St SE
Minneapolis, MN 55455