Sophia Vinogradov

Department Head and Professor


I am the Donald W. Hastings Endowed Chair in Psychiatry and Department Head of Psychiatry & Behavioral Sciences at the University of Minnesota (UMN) Medical School. Before joining UMN, I served as Vice Chair of the Department of Psychiatry at the University of California, San Francisco, and as Associate Chief of Staff for Mental Health at the San Francisco Veterans Affairs (VA) Medical Centre. 

I earned my MD at the Wayne State University School of Medicine in Detroit, Michigan. I further trained at the Palo Alto VA Medical Center and Stanford University, where I served as Chief Resident, followed by a fellowship in Psychiatric Neurosciences Research.

I direct a translational clinical neuroscience laboratory that focuses on cognitive dysfunction in psychosis. My lab studies neuroscience-informed cognitive training methods focusing on young adults in early psychosis with the goal of ameliorating cognition and focusing on functional outcomes. I lead a hub of the national EPINET (Early Psychosis Intervention Network) initiative, overseeing measurement-based specialty care in Minnesota and Iowa. I am also a co-PI on an NIMH Conte Center using computed psychiatry methods to study state representation dysfunction in psychosis.

I serve as Deputy Editor of the Schizophrenia Research Journal and am a fellow of the American College of Neuropharmacology. I lead the Clinical Neuroscience curriculum for the residency program. I have participated in the White House conference on “Video Games to Enhance Attention and Well-Being” and was a recipient of the National Alliance on Mental Illness (NAMI) National Research Award.

In the Media


BS, Faculte de Medecine, Universite Louis Pasteur
Major: Pre-Medical
MD, Wayne State University School of Medicine
Major: Medicine
BS, Yale University
Major: Pre-Medical

Fellowships, Residencies, and Visiting Engagements

Fellow, Fellowship
Palo Alto VA Medical Center and Stanford University
Palo Alto and Stanford, California
Resident, Residency
Stanford University
Stanford, California
Chief Resident, Residency
Palo Alto VA Medical Center and Stanford University
Palo Alto and Stanford, California
Internship, Internship
Stanford University
Stanford, California

Licensures and Certifications

DEA License,
California Medical Licensure,
Diplomate, American Board of Psychiatry and Neurology,
MN Board of Medical Practice,

Honors and Recognition

Laughlin Fellow Award, American College of Psychiatrists
NAMI National Scientific Research Award
Alexander Gralnick Award for Research in Schizophrenia, American Psychiatric Foundation
American Psychiatric Association Distinguished Fellow
APA/AACDP Research Mentorship Award
NAMI Exemplary Psychiatrist Award
Dean’s Distinguished Research Lecture and Award, University of Minnesota
V. Sagar Sethi, M.D. Mental Health Research Award

Professional Memberships

Psychiatric Research Society
American Associate of Chairs of Departments of Psychiatry
Schizophrenia International Research Society (SIRS), Treasurer
Women's Leadership Group
Scientific Program Committee
Society of Biological Psychiatry
American College of Neuropsychopharmacology , Fellow
Selected Publications

Selected Publications

Gadassi Polack, R., Bronstein, M. V., Questel, M., Edelman, A., Vinogradov, S., Kober, H., Joormann, J., & Everaert, J, 2023. Social interpretation inflexibility moderates emotional reactions to social situations in children and adolescents. Development and psychopathology. Advance online publication, Development and psychopathology 1-13.
Miley, K., Meyer-Kalos, P., Ma, S., Bond, D. J., Kummerfeld, E., & Vinogradov, S., 2023. Causal pathways to social and occupational functioning in the first episode of schizophrenia: uncovering unmet treatment needs. Psychological Medicine, 53 (5): 2041-2049.
Hua, J. P. Y., Loewy, R. L., Stuart, B., Fryer, S. L., Niendam, T. A., Carter, C. S., Vinogradov, S., & Mathalon, D. H., 2023. Cortical and subcortical brain morphometry abnormalities in youth at clinical high-risk for psychosis and individuals with early illness schizophrenia. Psychiatry research. Neuroimaging, 332 111653.
Hua, J. P. Y., Cummings, J., Roach, B., J., Fryer, S. L., Loewy, R. L., Stuart, B. K., Ford, J. M., Vinogradov, S., & Mathalon, D., 2023. Rich-club connectivity and structural connectome organization in youth at clinical high-risk for psychosis and individuals with early illness schizophrenia. Schizophrenia Research,
Vinogradov, S., Chafee, M. V., Lee, E., & Morishita, H., 2023. Psychosis spectrum illnesses as disorders of prefrontal critical period plasticity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 48 (1): 168-185.
Miley, K., Michalowski, M., Yu, F., Leng, E., McMorris, B. J., & Vinogradov, S., 2022. Predictive models for social functioning in healthy young adults: A machine learning study integrating neuroanatomical, cognitive, and behavioral data. Social Neuroscience, 17 (5): 414-427.
Jia, Y., Kudo, K., Hinkley, L. B. N., Fisher, M., Vinogradov, S., Nagarajan, S., & Subramaniam, K., 2022. Abnormal Information Flow in Schizophrenia Is Linked to Psychosis. Schizophrenia bulletin, 48 (6): 1384-1393.
Vinogradov, S., Hamid, A. A., & Redish, A. D., 2022. Etiopathogenic Models of Psychosis Spectrum Illnesses Must Resolve Four Key Features. Biological psychiatry, 92 (6): 514-522.
Baldwin, H., Radua, J., Antoniades, M., Haas, S. S., Vinogradov, S., et al., 2022. Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis. Translational psychiatry, 12 (1): 297.
Selected Presentations

Selected Presentations

Cognitive Remediation in Psychiatry Annual Meeting, Columbia University, 2023; New York, NY
American Psychological Association Convention, 2022; Minneapolis, MN
Grand Rounds, UT Health Psychiatry, 2022; San Antonio, TX
American College of Neuropsychopharmacology Annual Conference, 2022, Phoenix, AZ
RANZCP 2022 NZ Conference, 2022; Auckland, New Zealand
Grand Rounds, UCSF, 2022, San Francisco, CA
NCPA Annual Meeting, 2022; Asheville, NC
Big Ten Neuroscience Meeting, 2022; Iowa City, IA
Israel Society of Biological Psychiatry Annual Meeting, 2021; Tel-Aviv, Israel
SCBR Forum, 2021; Tokyo, Japan



Department of Psychiatry & Behavioral Sciences, F282/2A West Building, 2450 Riverside Avenue South, Minneapolis, MN 55454