Xavier Revelo

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Credentials

PhD

Bio

Dr. Revelo is an Assistant Professor in the Department of Integrative Biology & Physiology with expertise in inflammation and cardio-metabolic disease. His research explores the molecular and integrative biology of inflammation and metabolism with emphasis on the immune mechanisms that drive obesity, insulin resistance, fatty liver disease and cardiac dysfunction.

Research Summary

Our NIH-funded laboratory investigates the role of the immune system and inflammation in the pathophysiology of cardio-metabolic diseases such as diabetes, non-alcoholic fatty liver disease, and heart failure. As the outcome of inflammation largely depends on the balance between the pro- and anti-inflammatory functions, strategies that modulate these pathways will provide avenues to manage these diseases.
Our research program focuses on the following areas:
1. Mechanisms of hepatic and intestinal inflammation in non-alcoholic fatty liver disease, steatohepatitis, and liver cancer.
2. Immune mechanisms of cardiac remodeling
3. Mechanisms of obesity-related inflammation and food allergy
4. Anti-inflammatory mechanisms of exercise training