Matthew Slattery

Associate Professor

Research Summary

Whole genome sequencing has become increasingly straightforward in recent years, though our understanding of the regulatory genome – the noncoding portion of the genome dictating where, when, and to what level genes are expressed – remains incomplete. Research in the Slattery lab explores the mechanisms by which transcription factors interact with noncoding regulatory DNA elements, also known as enhancers, to influence cell fate decisions. We use an integrative approach centered on three major themes – DNA binding specificity, context-specific genomics, and cis-regulatory element dissection – to characterize gene regulatory networks controlling the response to environmental stress. Importantly, this approach also allows us to identify and test noncoding DNA variants linking the response to cell stress with various disease states.

Teaching Summary

Pharmacology (Neuropharmacology)

Mentoring/Advising: undergraduate students, graduate students, and post doctoral researchers


PhD, University of Wisconsin-Madison
Major: Pharmaceutical Sciences
BS, University of Wisconsin-Madison
Major: Pharmacology & Toxicology

Fellowships, Residencies, and Visiting Engagements

Postdoctoral Fellowship, Fellowship
Kirschtein National Research Service Awards
Postdoctoral Research Fellow, Fellowship
Columbia University and University of Chicago
Pre-Doctoral Fellowship, Fellowship
American Foundation for Pharmaceutical Education

Honors and Recognition

Basic Science Teacher of the Year - First Year Medical Students, University of Minnesota Medical School, Duluth Campus
Postdoctoral Student Mentor Award, Society of Toxicology, Molecular and Systems Biology Specialty Section
Top Ten Paper in Regulatory Systems Genomics 2011 (RECOMB)
Oscar Rennebohm Award for Ph.D. Dissertation, University of Wisconsin
Zaman Saroya Graduate Student Award, University of Wisconsin
Covance Laboratories Award for Undergraduate Research
UW College of Agriculture & Life Sciences Ferdinand Plaenert Award
Wisconsin Academic Excellence Higher Education Scholarship

Professional Memberships

Society for Redox Biology and Medicine
UMN developmental Biology Center, Member
Genetics Society of America



Department of Biomedical Sciences
Smed 255
1035 University Drive
Duluth, MN 55812
(218) 726-7223