Genome Engineering

We create and deploy genetically modified cells while educating the next generation of genetic engineers.

Center for Genome Engineering

Established in 1998 The Center for Genome Engineering brings together departments across multiple campuses to advance engineered cell therapies through research and clinical objectives.

PhDs and MDs across the University gather together to collaborate with a multidisciplinary approach. The coming together of complementary expertises has not only fueled research, but also facilitated clinical trials and launched biomedical start-up companies.

Learn more about our research or contact: umn-cge@umn.edu 

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Genome Engineering Resources at the University of Minnesota

The University of Minnesota Viral Vector and Cloning Core (VVCC) was established in May 2017 to help meet the needs of investigators requiring DNA and viral vector tools for their research programs. Since then, we have completed 400+ custom cloning and 1000+ viral packaging projects for 70+ different clients across the University of Minnesota Medical School, College of Pharmacy, School of Dentistry, College of Veterinary Medicine, College of Science and Engineering, and College of Biological Sciences. 


The Genome Engineering Shared Resource (GESR) is a Core dedicated for the use of all Masonic Cancer Center members. Its purpose is to provide (at cost) state-of-the-art genome editing services for human cell lines. The GESR will initially have the capacity to make standard knockouts and knockins for your favorite gene in your favorite cell line. Ultimately GESR will provide services for making conditional alleles and epitope tagging endogenous genes as well as carrying out whole genome knockout screens.


Provides genomics research services committed to advancing genomics in Minnesota. Maintains and acquires state-of-the-art instrumentation and offers an array of services including sequencing, expression, genotyping, nucleic acid extraction and related support. Strives to keep pace with the ever-broadening world of “omics” technologies (genomics, epigenomics, metabolomics), and to expand our role at the University and the wider biotech community.


The Mouse Genetics Laboratory (MGL) provides a comprehensive range of mouse genomic editing and embryo manipulation services as a research resource for the Office of Academic Clinical Affairs.